Cdh3 - cadherin 3 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 116777

Summary

Predicted to enable Cadherin binding activity and calcium ion binding activity. Involved in response to xenobiotic stimulus and wound healing. Located in cytoplasm and plasma membrane. Human ortholog(s) of this gene implicated in congenital hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome. Orthologous to human CDH3 (Cadherin 3). [provided by Alliance of Genome Resources, Apr 2022]

Cdh3 Products (1)

mRNA Protein Name
NM_053938.2 NP_446390.2 cadherin-3 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
17298545 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cadherin-3

  • cadherin 3, type 1, P-cadherin (placental)

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P990645 PF-03732010 99.68% Phase 1
HY-P991341 FF-21101 Inhibitor 96.77% Phase 1

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W1124025 (5-Cl)-DXd / Unkown
HY-RS02325 CDH15 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02336 CDH3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18343 Cdh3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24822 Cdh3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991342 CQY684 Inhibitor 97.60% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdh3 NCBI NCBI:1001