(5-Cl)-DXd
(5-Cl)-DXd, a derivative of DXd (HY-13631), is a cytotoxic drug that can be used in synthesis of CDH3-targeting antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- CAS No.: 2813268-45-8
- Formula: C26H24ClN3O6
- Molecular Weight:509.94
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2813268-45-8
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Appearance Solid
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Molecular Weight 509.94
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Formula C26H24ClN3O6
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Color Light yellow to yellow
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SMILES
OCC(N[C@@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(Cl)=C(C)C(CC1)=C62)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 50 mg/mL (98.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9610 mL | 9.8051 mL | 19.6102 mL | 49.0254 mL |
| 5 mM | 0.3922 mL | 1.9610 mL | 3.9220 mL | 9.8051 mL | |
| 10 mM | 0.1961 mL | 0.9805 mL | 1.9610 mL | 4.9025 mL | |
| 15 mM | 0.1307 mL | 0.6537 mL | 1.3073 mL | 3.2684 mL | |
| 20 mM | 0.0981 mL | 0.4903 mL | 0.9805 mL | 2.4513 mL | |
| 25 mM | 0.0784 mL | 0.3922 mL | 0.7844 mL | 1.9610 mL | |
| 30 mM | 0.0654 mL | 0.3268 mL | 0.6537 mL | 1.6342 mL | |
| 40 mM | 0.0490 mL | 0.2451 mL | 0.4903 mL | 1.2256 mL | |
| 50 mM | 0.0392 mL | 0.1961 mL | 0.3922 mL | 0.9805 mL | |
| 60 mM | 0.0327 mL | 0.1634 mL | 0.3268 mL | 0.8171 mL | |
| 80 mM | 0.0245 mL | 0.1226 mL | 0.2451 mL | 0.6128 mL |
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