Ccl17 - C-C motif chemokine ligand 17 Gene

Also Known as Tarc; Scya17

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 117518

Summary

Enables CCR4 Chemokine Receptor binding activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; leukocyte chemotaxis; and positive regulation of ERK1 and ERK2 cascade. Predicted to act upstream of or within negative regulation of myoblast differentiation. Predicted to be active in extracellular space. Biomarker of anti-basement membrane glomerulonephritis; asthma; pneumonia; and pulmonary fibrosis. Orthologous to human CCL17 (C-C motif chemokine ligand 17). [provided by Alliance of Genome Resources, Apr 2022]

Ccl17 Products (1)

mRNA Protein Name
NM_057151.2 NP_476492.2 C-C motif chemokine 17 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables CCR4 chemokine receptor binding IPI
IPI: Inferred from physical interaction
18856064 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

C-C motif chemokine 17

  • chemokine (C-C motif) ligand 17

  • small inducible cytokine subfamily A (Cys-Cys), member 17

Recombinant Ccl17 Proteins

Cat. No. Product Name Accession Purity
HY-P71902 TARC/CCL17 Protein, Rat (His) Q9ERE0 (A24-L93) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-148494 Tivumecirnon Antagonist 99.48% Phase 2
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P990982 Denrakibart Inhibitor 98.24% Phase 2

Pre-clinical Phase

Bioactive Molecules (13)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P3982 CKLF1-C19 Chemical 99.11% Unkown
HY-176949 STAT6-IN-10 Inhibitor 98.81% Unkown
HY-181006 TSLP modulator-1 Inhibitor 99.61% Unkown
HY-119050 Anti-inflammatory agent 87 Inhibitor / Unkown
HY-175650 STAT6-IN-9 Inhibitor 98.11% Unkown
HY-182564 ST45177901 Antagonist / Unkown
HY-185073 STAT6-IN-11 Inhibitor / Unkown
HY-185144 CCL17-IN-1 / Unkown
HY-185145 CCL17-IN-2 / Unkown
HY-RS02086 CCL17 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174766 Human CCL17 mRNA / Unkown
HY-RS16826 Ccl17 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23268 Ccl17 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992474 TAVO101 96.62% Unkown
HY-P992378 HZ-1127 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ccl17 NCBI NCBI:6361