Il10ra - interleukin 10 receptor subunit alpha Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 117539

Summary

Enables interleukin-10 binding activity and interleukin-10 receptor activity. Involved in regulation of synapse organization and response to lipopolysaccharide. Colocalizes with plasma membrane. Human ortholog(s) of this gene implicated in inflammatory bowel disease 28. Orthologous to human IL10RA (interleukin 10 receptor subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Il10ra Products (1)

mRNA Protein Name
NM_057193.2 NP_476541.2 interleukin-10 receptor subunit alpha precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables interleukin-10 binding IMP
IMP: Inferred from mutant phenotype
19428551 RGD
enables interleukin-10 binding IPI
IPI: Inferred from physical interaction
12405978 RGD
enables interleukin-10 receptor activity IMP
IMP: Inferred from mutant phenotype
19428551 RGD
Biological Process GO Annotation Evidence References Source
involved in regulation of synapse organization IMP
IMP: Inferred from mutant phenotype
24278397 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
12010759 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-10 receptor subunit alpha

  • interleukin 10 receptor, alpha

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06673 IL10RA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174645 Human IL10RA mRNA / Unkown
HY-RS17431 Il10ra Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23886 Il10ra Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990776 Vimekofusp / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il10ra NCBI NCBI:3587