Apba2 - amyloid beta (A4) precursor protein-binding, family A, member 2 Gene

Also Known as X11L; XllL; mXllL; X11-like

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11784

Summary

Predicted to enable amyloid-beta binding activity and identical protein binding activity. Involved in regulation of synaptic vesicle exocytosis. Acts upstream of or within several processes, including chemical synaptic transmission; in utero embryonic development; and locomotory behavior. Located in Schaffer collateral - CA1 synapse. Is expressed in several structures, including alimentary system; nervous system; respiratory system; sensory organ; and skeleton. Orthologous to human APBA2 (amyloid beta precursor protein binding family A member 2). [provided by Alliance of Genome Resources, Apr 2022]

Apba2 Products (19)

mRNA Protein Name
NM_001291166.2 NP_001278095.1 amyloid-beta A4 precursor protein-binding family A member 2 isoform a
NM_001291167.2 NP_001278096.1 amyloid-beta A4 precursor protein-binding family A member 2 isoform a
NM_001411931.1 NP_001398860.1 amyloid-beta A4 precursor protein-binding family A member 2 isoform a
NM_001411932.1 NP_001398861.1 amyloid-beta A4 precursor protein-binding family A member 2 isoform a
NM_001411933.1 NP_001398862.1 amyloid-beta A4 precursor protein-binding family A member 2 isoform a
NM_001411934.1 NP_001398863.1 amyloid-beta A4 precursor protein-binding family A member 2 isoform a
NM_001411935.1 NP_001398864.1 amyloid-beta A4 precursor protein-binding family A member 2 isoform a
NM_001411936.1 NP_001398865.1 amyloid-beta A4 precursor protein-binding family A member 2 isoform b
NM_001411937.1 NP_001398866.1 amyloid-beta A4 precursor protein-binding family A member 2 isoform b
NM_001411938.1 NP_001398867.1 amyloid-beta A4 precursor protein-binding family A member 2 isoform b
NM_001411939.1 NP_001398868.1 amyloid-beta A4 precursor protein-binding family A member 2 isoform b
NM_001411940.1 NP_001398869.1 amyloid-beta A4 precursor protein-binding family A member 2 isoform b
NM_001411941.1 NP_001398870.1 amyloid-beta A4 precursor protein-binding family A member 2 isoform b
NM_001411942.1 NP_001398871.1 amyloid-beta A4 precursor protein-binding family A member 2 isoform c
NM_001411943.1 NP_001398872.1 amyloid-beta A4 precursor protein-binding family A member 2 isoform c
NM_001411944.1 NP_001398873.1 amyloid-beta A4 precursor protein-binding family A member 2 isoform c
NM_001411945.1 NP_001398874.1 amyloid-beta A4 precursor protein-binding family A member 2 isoform d
NM_001411946.1 NP_001398875.1 amyloid-beta A4 precursor protein-binding family A member 2 isoform d
NM_007461.3 NP_031487.1 amyloid-beta A4 precursor protein-binding family A member 2 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10833507 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within chemical synaptic transmission IGI
IGI: Inferred from genetic interaction
17167098 MGI
acts upstream of or within in utero embryonic development IGI
IGI: Inferred from genetic interaction
17167098 MGI
acts upstream of or within locomotory behavior IGI
IGI: Inferred from genetic interaction
17167098 MGI
acts upstream of or within multicellular organism growth IGI
IGI: Inferred from genetic interaction
17167098 MGI
involved in presynaptic modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
17167098 MGI
involved in presynaptic modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
17167098 MGI
acts upstream of or within regulation of gene expression IGI
IGI: Inferred from genetic interaction
17167098 MGI
Cellular Component GO Annotation Evidence References Source
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
17167098 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: Inferred from mutant phenotype
17167098 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

amyloid-beta A4 precursor protein-binding family A member 2

  • Mint 2

  • adapter protein X11beta

  • mint-2

  • neuron-specific X11L protein

  • neuronal Munc18-1-interacting protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00803 APBA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22391 Apba2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28915 Apba2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Apba2 NCBI NCBI:321