Arsa - arylsulfatase A Gene

Also Known as ASA; As2; AS-A; As-2; TISP73

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11883

Summary

Predicted to enable arylsulfatase activity and calcium ion binding activity. Acts upstream of or within binding activity of sperm to zona pellucida. Located in plasma membrane. Is integral component of membrane. Is expressed in brain and genitourinary system. Used to study metachromatic leukodystrophy. Human ortholog(s) of this gene implicated in metachromatic leukodystrophy. Orthologous to human ARSA (arylsulfatase A). [provided by Alliance of Genome Resources, Apr 2022]

Arsa Products (1)

mRNA Protein Name
NM_009713.4 NP_033843.2 arylsulfatase A precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within binding of sperm to zona pellucida IMP
IMP: Inferred from mutant phenotype
12080020 MGI
Cellular Component GO Annotation Evidence References Source
located in membrane IDA
IDA: Inferred from direct assay
12080020 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
12080020 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

arylsulfatase A

  • cerebroside-sulfatase

Recombinant Arsa Proteins

Cat. No. Product Name Accession Purity
HY-P75499 Arylsulfatase A/ARSA Protein, Mouse (HEK293, His) P50428/NP_033843.2 (S18-S506) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-123650 FSBA hydrochloride 99.06% Unkown
HY-RS01034 ARSA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18745 Arsa Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25232 Arsa Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arsa NCBI NCBI:410