Avpr2 - arginine vasopressin receptor 2 Gene

Mus musculus

Also known as DI1; DIR; ND1; V2R; ADHR; VPV2R

Gene ID: 12000 | Gene type: protein coding

About Avpr2

Chromosome X: 72,935,708-72,939,108 forward strand.GRCm39:CM001013.3

This gene has 4 transcripts (splice variants), 233 orthologues, 16 paralogues and is associated with 12 phenotypes. Biased expression in kidney adult (RPKM 17.2), thymus adult (RPKM 4.6) and 1 other tissue.

Summary

This gene encodes a member of the G-protein coupled receptor 1 family and the vasopressin/Oxytocin Receptor subfamily. The encoded protein is an arginine Vasopressin Receptor which, when stimulated, activates the Gs protein/adenylyl cyclase signaling cascade and is involved in water and electrolyte homeostasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Avpr2 Products(3)

mRNA	Protein	Name
NM_019404.2	NP_062277.1	vasopressin V2 receptor isoform a
NM_001276298.1	NP_001263227.1	vasopressin V2 receptor isoform b
NM_001276299.1	NP_001263228.1	vasopressin V2 receptor isoform c

Avpr2 Protein Structure

7tmA_V2R

0
100
200
300
371 a.a.

Protein Preferred Names

Protein Names

vasopressin V2 receptor

antidiuretic hormone receptor	nephrogenic diabetes insipidus
renal-type arginine vasopressin receptor

Related Agents

Approval

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P0049A	Argipressin diacetate		/	Unkown

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS01287	AVPR2 Human Pre-designed siRNA Set A	/	Unkown
HY-RS01288	Avpr2 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS01289	Avpr2 Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Avpr2	NCBI	NCBI:554

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