2. Gene
  3. TMEM219 - transmembrane protein 219 Gene

TMEM219 - transmembrane protein 219 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as IGFBP-3R

Gene ID: 124446 | Gene type: protein coding

About TMEM219

This gene has 8 transcripts (splice variants), 166 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 42.5), small intestine (RPKM 28.6) and 25 other tissues.

Summary

Predicted to be involved in apoptotic process. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM219 Products(5)

mRNA Protein Name
NM_001083613.2 NP_001077082.1 insulin-like growth factor-binding protein 3 receptor isoform 1 precursor
NM_001369688.1 NP_001356617.1 insulin-like growth factor-binding protein 3 receptor isoform 1 precursor
NM_001369689.1 NP_001356618.1 insulin-like growth factor-binding protein 3 receptor isoform 2 precursor
NM_001369690.1 NP_001356619.1 insulin-like growth factor-binding protein 3 receptor isoform 3 precursor
NM_194280.4 NP_919256.1 insulin-like growth factor-binding protein 3 receptor isoform 1 precursor

TMEM219 Protein Structure

TMEM219

TMEM219: Transmembrane 219 (10 - 175)

  • 0
  • 100
  • 200
  • 240 a.a.
Protein Preferred Names Protein Names

insulin-like growth factor-binding protein 3 receptor

testicular tissue protein Li 203

Recombinant TMEM219 Proteins

Cat. No. Product Name Accession Purity
HY-P77962 TMEM219/IGFBP-3R Protein, Human (HEK293, Fc) Q86XT9 (S39-R204) ≥95%

Related Diseases

Diseases Alias
Hermansky-Pudlak Syndrome

Hps

Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial Cells

Hermanski-Pudlak Syndrome

Hermansky Pudlak Syndrome

Platelet Storage Pool Deficiency
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14700 TMEM219 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus TMEM219 RGD RGD:1560566
Bos taurus TMEM219 VGNC VGNC:36041
Mus musculus TMEM219 MGD MGI:1915992
Canis familiaris TMEM219 VGNC VGNC:47535
Felis catus TMEM219 VGNC VGNC:66315
Macaca mulatta TMEM219 VGNC VGNC:99618
Others TMEM219 NCBI