2. Gene
  3. Ccr6 - chemokine (C-C motif) receptor 6 Gene

Ccr6 - chemokine (C-C motif) receptor 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as CCR-6; KY411; Cmkbr6; CC-CKR-6

Gene ID: 12458 | Gene type: protein coding

About Ccr6

Chromosome 17: 8,454,875-8,475,973 forward strand.GRCm39:CM001010.3

This gene has 9 transcripts (splice variants), 299 orthologues, 25 paralogues and is associated with 58 phenotypes. Biased expression in spleen adult (RPKM 9.8), mammary gland adult (RPKM 4.1) and 5 other tissues.

Summary

Enables C-C chemokine binding activity and C-C Chemokine Receptor activity. Involved in several processes, including immune system development; leukocyte migration; and regulation of cell motility. Located in external side of plasma membrane; sperm plasma membrane; and sperm principal piece. Is expressed in several structures, including central nervous system; gut; immune system; male reproductive gland or organ; and retina. Orthologous to human CCR6 (C-C motif Chemokine Receptor 6). [provided by Alliance of Genome Resources, Apr 2022]

Ccr6 Products(7)

mRNA Protein Name
NM_001190335.1 NP_001177264.1 C-C chemokine receptor type 6 isoform A
NM_001190334.1 NP_001177263.1 C-C chemokine receptor type 6 isoform A
NM_001190336.1 NP_001177265.1 C-C chemokine receptor type 6 isoform A
NM_001190333.1 NP_001177262.1 C-C chemokine receptor type 6 isoform A
NM_009835.4 NP_033965.1 C-C chemokine receptor type 6 isoform A
NM_001190338.1 NP_001177267.1 C-C chemokine receptor type 6 isoform B
NM_001190337.1 NP_001177266.1 C-C chemokine receptor type 6 isoform A

Ccr6 Protein Structure

7tmA_CCR6

7tmA_CCR6: cd15172 (38 - 65)

7tmA_CCR6

7tmA_CCR6: cd15172 (38 - 318)

7tmA_CCR6

7tmA_CCR6: cd15172 (72 - 97)

7tmA_CCR6

7tmA_CCR6: cd15172 (109 - 139)

7tmA_CCR6

7tmA_CCR6: cd15172 (153 - 175)

7tmA_CCR6

7tmA_CCR6: cd15172 (202 - 231)

7tmA_CCR6

7tmA_CCR6: cd15172 (238 - 268)

7tmA_CCR6

7tmA_CCR6: cd15172 (286 - 311)

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  • 367 a.a.
Protein Preferred Names Protein Names

C-C chemokine receptor type 6

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-148531 PF-07054894 Inhibitor 99.12% Phase 1
Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-151435 CCR6 antagonist 1 Antagonist 99.55% Unkown
HY-112701 CCR6 inhibitor 1 Inhibitor 99.60% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ccr6 NCBI NCBI:1235