Entpd2 - ectonucleoside triphosphate diphosphohydrolase 2 Gene

Also Known as Cd39l1; NTPDase2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12496

Summary

Enables nucleoside-diphosphatase activity and nucleoside-triphosphatase activity. Acts upstream of or within G protein-coupled receptor signaling pathway; platelet activation; and purine ribonucleoside diphosphate catabolic process. Located in basement membrane and plasma membrane. Is expressed in nervous system. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human ENTPD2 (ectonucleoside triphosphate diphosphohydrolase 2). [provided by Alliance of Genome Resources, Apr 2022]

Entpd2 Products (1)

mRNA Protein Name
NM_009849.2 NP_033979.2 ectonucleoside triphosphate diphosphohydrolase 2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables nucleoside diphosphate phosphatase activity IDA
IDA: Inferred from direct assay
11929769 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11591653 MGI
enables ribonucleoside triphosphate phosphatase activity IDA
IDA: Inferred from direct assay
11929769 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
11929769 MGI
acts upstream of or within platelet activation IDA
IDA: Inferred from direct assay
11929769 MGI
acts upstream of or within purine ribonucleoside diphosphate catabolic process IDA
IDA: Inferred from direct assay
11929769 MGI
Cellular Component GO Annotation Evidence References Source
located in basement membrane IDA
IDA: Inferred from direct assay
11929769 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
23010799 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ectonucleoside triphosphate diphosphohydrolase 2

  • CD39 antigen-like 1

  • NTPDase 2

  • ecto-ATP diphosphohydrolase 2

  • ecto-ATPDase 2

  • ecto-ATPase 2

Recombinant Entpd2 Proteins

Cat. No. Product Name Accession Purity
HY-P72729 CD39L1/ENTPD2 Protein, Mouse (HEK293, His) O55026 (C26-S462) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04396 ENTPD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18863 Entpd2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25355 Entpd2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991917 Anti-ENTPD2 Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Entpd2 NCBI NCBI:954