Csf2rb - colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) Gene

Also Known as Bc; Il3r; AIC2B; Il3rb; Il5rb; CDw131; Il3rb1; Csf2rb1; Csfgmrb

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12983

Summary

Predicted to enable cytokine receptor activity. Acts upstream of or within cytokine-mediated signaling pathway and regulation of cell growth. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including bone marrow; cardiovascular system mesenchyme; dorsal aorta; genitourinary system; and yolk sac. Used to study pulmonary alveolar proteinosis. Human ortholog(s) of this gene implicated in pulmonary alveolar proteinosis. Orthologous to human CSF2RB (colony stimulating factor 2 receptor subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Csf2rb Products (2)

mRNA Protein Name
NM_001358854.1 NP_001345783.1 cytokine receptor common subunit beta precursor
NM_007780.4 NP_031806.3 cytokine receptor common subunit beta precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19098920 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cytokine-mediated signaling pathway IDA
IDA: Inferred from direct assay
19109256 MGI
acts upstream of or within regulation of cell growth IGI
IGI: Inferred from genetic interaction
19109256 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytokine receptor common subunit beta

  • CD131 antigen

  • GM-CSF/IL-3/IL-5 receptor common beta subunit

  • GM-CSF/IL-3/IL-5 receptor common beta-chain

  • beta c

  • colony stimulating factor 2 receptor, beta 1, low-affinity (granulocyte-macrophage)

  • common beta chain

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03233 CSF2RB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18705 Csf2rb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25192 Csf2rb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990094 Trabikibart 99.17% Unkown
HY-P990975 Birinkibart 98.26% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Csf2rb NCBI NCBI:1439