Ebf1 - early B cell factor 1 Gene

Also Known as Ebf; OE-1; Olf1; O/E-1; Olf-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13591

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within positive regulation of transcription, DNA-templated. Located in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; integumental system; limb mesenchyme; and sensory organ. Used to study lipodystrophy. Orthologous to human EBF1 (EBF transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Ebf1 Products (12)

mRNA Protein Name
NM_001290709.1 NP_001277638.1 transcription factor COE1 isoform 1
NM_001290710.1 NP_001277639.1 transcription factor COE1 isoform 3
NM_001290711.1 NP_001277640.1 transcription factor COE1 isoform 4
NM_001362569.1 NP_001349498.1 transcription factor COE1 isoform 8
NM_001362571.1 NP_001349500.1 transcription factor COE1 isoform 5
NM_001362574.1 NP_001349503.1 transcription factor COE1 isoform 6
NM_001362575.1 NP_001349504.1 transcription factor COE1 isoform 7
NM_001362576.1 NP_001349505.1 transcription factor COE1 isoform 9
NM_001362577.1 NP_001349506.1 transcription factor COE1 isoform 9
NM_001362578.1 NP_001349507.1 transcription factor COE1 isoform 10
NM_001362579.1 NP_001349508.1 transcription factor COE1 isoform 10
NM_007897.3 NP_031923.1 transcription factor COE1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
14594818 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
12446773 MGI
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
14594818 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
12446773 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12139918 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
12139918 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
12446773 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
14594818 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
14594818 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor COE1

  • early B-cell factor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04124 EBF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19324 Ebf1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25815 Ebf1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ebf1 NCBI NCBI:1879