EBF1 - EBF transcription factor 1 Gene

Homo sapiens

Also known as EBF; COE1; OLF1; O/E-1

Gene ID: 1879 | Gene type: protein coding

About EBF1

Cytogenetic location: 5q33.3 Genomic coordinates (GRCh38): 5:158,695,920-159,099,916 (from NCBI)

This gene has 11 transcripts (splice variants), 300 orthologues, 3 paralogues and is associated with 83 phenotypes. Broad expression in fat (RPKM 3.2), placenta (RPKM 0.8) and 17 other tissues.

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of transcription, DNA-templated. Predicted to be located in nucleus. Predicted to be part of chromatin. [provided by Alliance of Genome Resources, Apr 2022]

EBF1 Products(15)

mRNA	Protein	Name
NM_001290360.3	NP_001277289.1	transcription factor COE1 isoform 1
NM_001324101.2	NP_001311030.1	transcription factor COE1 isoform 4
NM_001324103.2	NP_001311032.1	transcription factor COE1 isoform 5
NM_001324106.2	NP_001311035.1	transcription factor COE1 isoform 6
NM_001324107.2	NP_001311036.1	transcription factor COE1 isoform 7
NM_001324108.2	NP_001311037.1	transcription factor COE1 isoform 8
NM_001324109.2	NP_001311038.1	transcription factor COE1 isoform 9
NM_001324111.2	NP_001311040.1	transcription factor COE1 isoform 10
NM_001364155.2	NP_001351084.1	transcription factor COE1 isoform 11
NM_001364156.2	NP_001351085.1	transcription factor COE1 isoform 13
NM_001364157.2	NP_001351086.1	transcription factor COE1 isoform 14
NM_001364158.2	NP_001351087.1	transcription factor COE1 isoform 15
NM_001364159.2	NP_001351088.1	transcription factor COE1 isoform 16
NM_024007.5	NP_076870.1	transcription factor COE1 isoform 2
NM_182708.3	NP_874367.1	transcription factor COE1 isoform 3

EBF1 Protein Structure

TIG

0
100
200
300
400
500
591 a.a.

Protein Preferred Names

Protein Names

transcription factor COE1

Collier, Olf and EBF transcription factor 1

Related Diseases

Diseases

Alias

Plasmacytoma

Solitary Plasmacytoma	Solitary Myeloma
Myeloma - Solitary	Myeloma, Solitary
Plasmacytoma - Category	Solitary Osseous Plasmacytoma
Solitary Plasmacytoma Without Mention Of Remission	Localised Malignant Plasma Cell Tumour Nos
Plasmacytoma Nos

Breast Abscess

Abscess Of Breast

B-Lymphoblastic Leukemia/Lymphoma With Bcr-Abl1

B-All With Bcr-Abl1	B-Lymphoblastic Leukemia/Lymphoma With T(9
22)(Q34.1	Q11.2)
Bcr-Abl1	B Lymphoblastic Leukemia/Lymphoma With T(9
22)(Q34.1	Q11.2)
Bcr-Abl1

Postpartum Depression

Maternity Blues	Postnatal Depression
Depression, Postpartum	Post-Partum Depression
Depression Postpartum

B-Lymphoblastic Leukemia/Lymphoma With Iamp21

B-All With Iamp21

Intrachromosomal Amplification Of Chromosome 21

Endogenous Depression

Clinical Depression	Unipolar Depression
Depressive Disorder

Tetanus Neonatorum

Neonatal Tetanus	NNT
Trismus Neonatorum	Newborn Trismus

Prion Disease

Spongiform Encephalopathy	Transmissible Spongiform Encephalopathies
Prion Diseases	Prion Disease Pathway
Transmissible Spongiform Encephalopathy	Prion Induced Disorder
Prion Protein Disease	Inherited Human Transmissible Spongiform Encephalopathies
Prion Protein Diseases	Prion-Associated Disorders
Prion-Induced Disorders	Transmissible Dementias
Tses	Human Prion Disease
Tse	Encephalopathy, Transmissible Spongiform
Prion Disease, Susceptibility To	Spongiform Encephalopathies
Human Transmissible Spongiform Encephalopathies, Inherited

B-Lymphoblastic Leukemia/Lymphoma

B Lymphoblastic Leukemia/Lymphoma	B-All
Precursor B Lymphoblastic Lymphoma/Leukemia	C-All
Lymphoblastic Lymphoma, Nos	Common Precursor B All
Lymphoblastic B-Cell Lymphoma	Pro-B All
B-Precursor Lymphoma	Lbl - [Lymphoblastic Lymphoma]

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04124	EBF1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	EBF1	VGNC	VGNC:50162
Macaca mulatta	EBF1	VGNC	VGNC:72030
Mus musculus	EBF1	MGD	MGI:95275
Rattus norvegicus	EBF1	RGD	RGD:620953
Felis catus	EBF1	VGNC	VGNC:61703
Canis familiaris	EBF1	VGNC	VGNC:40175