Efnb1 - ephrin B1 Gene

Also Known as Epl2; EFL-3; Elk-L; Eplg2; Lerk2; Stra1; Cek5-L; LERK-2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13641

Summary

This gene encodes a membrane protein that acts as a ligand for Eph family receptors. Signalling occurs bidirectionally in both the cell containing the receptor and the cell expressing this protein. Activity of this protein is important in neuronal axon growth and Other developmental processes. [provided by RefSeq, May 2015]

Efnb1 Products (1)

mRNA Protein Name
NM_010110.5 NP_034240.1 ephrin-B1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ephrin receptor binding IPI
IPI: Inferred from physical interaction
14988728 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
9920925 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within T cell costimulation IDA
IDA: Inferred from direct assay
15599401 MGI
acts upstream of T cell proliferation IDA
IDA: Inferred from direct assay
15502157 MGI
acts upstream of or within axon guidance IMP
IMP: Inferred from mutant phenotype
11731465 MGI
acts upstream of or within embryonic pattern specification IMP
IMP: Inferred from mutant phenotype
15037550 MGI
acts upstream of or within neural crest cell migration IMP
IMP: Inferred from mutant phenotype
15037550 MGI
acts upstream of or within positive regulation of T cell proliferation IDA
IDA: Inferred from direct assay
15502157 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
19515908 MGI
located in membrane raft IDA
IDA: Inferred from direct assay
10197531 MGI
located in nucleus IDA
IDA: Inferred from direct assay
19515908 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ephrin-B1

  • CEK5 receptor ligand

  • Cek ligand

  • ELK ligand

  • EPH-related receptor tyrosine kinase ligand 2

  • stimulated by retinoic acid gene 1 protein

Recombinant Efnb1 Proteins

Cat. No. Product Name Accession Purity
HY-P70374 Ephrin-B1/EFNB1 Protein, Mouse (HEK293, Fc-His) P52795 (K30-S229) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P73027 Ephrin-B1/EFNB1 Protein, Mouse (HEK293, Fc) NP_034240.1 (K30-S229) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P73028 Ephrin-B1/EFNB1 Protein, Mouse (HEK293, His) P52795/NP_034240.1 (K30-S229) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04197 EFNB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17977 Efnb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24448 Efnb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Efnb1 NCBI NCBI:1947