Emx2 - empty spiracles homeobox 2 Gene

Also Known as Pdo

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13797

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including anterior/posterior pattern specification; forebrain development; and ureter morphogenesis. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; future brain; genitourinary system; hindlimb phalanx; and nose. Orthologous to human EMX2 (empty spiracles homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]

Emx2 Products (1)

mRNA Protein Name
NM_010132.2 NP_034262.2 homeobox protein EMX2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within anterior/posterior pattern specification IGI
IGI: Inferred from genetic interaction
15917450 MGI
acts upstream of or within anterior/posterior pattern specification IMP
IMP: Inferred from mutant phenotype
12196586 MGI
acts upstream of or within brain development IMP
IMP: Inferred from mutant phenotype
12091317 MGI
acts upstream of or within cell proliferation in forebrain IMP
IMP: Inferred from mutant phenotype
10729342 MGI
acts upstream of or within cerebral cortex development IGI
IGI: Inferred from genetic interaction
12764040 MGI
acts upstream of or within cerebral cortex regionalization IGI
IGI: Inferred from genetic interaction
15147765 MGI
acts upstream of or within cerebral cortex regionalization IMP
IMP: Inferred from mutant phenotype
12764040 MGI
acts upstream of or within dentate gyrus development IMP
IMP: Inferred from mutant phenotype
10729342 MGI
acts upstream of or within forebrain cell migration IMP
IMP: Inferred from mutant phenotype
10729342 MGI
acts upstream of or within forebrain development IGI
IGI: Inferred from genetic interaction
15917450 MGI
acts upstream of or within forebrain development IMP
IMP: Inferred from mutant phenotype
15294144 MGI
acts upstream of or within neuron differentiation IMP
IMP: Inferred from mutant phenotype
12561075 MGI
acts upstream of or within neuron migration IMP
IMP: Inferred from mutant phenotype
10729342 MGI
acts upstream of or within regulation of gene expression IMP
IMP: Inferred from mutant phenotype
12764040 MGI
acts upstream of or within response to xenobiotic stimulus IDA
IDA: Inferred from direct assay
9098922 MGI
involved in stereocilium bundle organization IMP
IMP: Inferred from mutant phenotype
34001891 MGI
acts upstream of or within ureter morphogenesis IGI
IGI: Inferred from genetic interaction
21731775 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein EMX2

  • empty spiracles homolog 2

  • empty spiracles-like protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04364 EMX2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20728 Emx2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27240 Emx2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Emx2 NCBI NCBI:2018