Stom - stomatin Gene

Also Known as Epb7.2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13830

Summary

Enables protein homodimerization activity. Involved in several processes, including positive regulation by host of viral genome replication; positive regulation of protein targeting to membrane; and regulation of acid-sensing ion channel activity. Located in mitochondrion and perinuclear region of cytoplasm. Is integral component of plasma membrane. Is expressed in bladder; gut; and liver lobe. Orthologous to human STOM (stomatin). [provided by Alliance of Genome Resources, Apr 2022]

Stom Products (1)

mRNA Protein Name
NM_013515.2 NP_038543.1 stomatin

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
22850675 MGI
enables ion channel inhibitor activity IDA
IDA: Inferred from direct assay
22850675 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
22850675 MGI
enables protein homodimerization activity IPI
IPI: Inferred from physical interaction
22850675 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation by host of viral genome replication IMP
IMP: Inferred from mutant phenotype
25262680 MGI
involved in positive regulation of protein targeting to membrane IMP
IMP: Inferred from mutant phenotype
25262680 MGI
involved in positive regulation of viral process IMP
IMP: Inferred from mutant phenotype
25262680 MGI
involved in regulation of monoatomic ion transmembrane transport IDA
IDA: Inferred from direct assay
22850675 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
25262680 MGI
located in mitochondrion IDA
IDA: Inferred from direct assay
25262680 MGI
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
25262680 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
22850675 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

stomatin

  • erythrocyte band 7 integral membrane protein

  • erythrocyte membrane protein band 7.2

  • erythrocyte protein band 7.2

  • erythrocyte protein band 7.2

  • protein 7.2b

  • protein 7.2b

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-17015A Peramivir 99.94% Unkown

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13949 STOM Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16927 Stom Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23370 Stom Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Stom NCBI NCBI:2040