Nr2f6 - nuclear receptor subfamily 2, group F, member 6 Gene

Also Known as EAR2; Erbal2; COUP-TF3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13864

Summary

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within detection of temperature stimulus involved in sensory perception of pain; entrainment of circadian clock by photoperiod; and neuron development. Predicted to be located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system; and sensory organ. Orthologous to human NR2F6 (nuclear receptor subfamily 2 group F member 6). [provided by Alliance of Genome Resources, Apr 2022]

Nr2f6 Products (1)

mRNA Protein Name
NM_010150.2 NP_034280.2 nuclear receptor subfamily 2 group F member 6

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
12690040 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
12690040 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
21247419 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within detection of temperature stimulus involved in sensory perception of pain IMP
IMP: Inferred from mutant phenotype
15741322 MGI
acts upstream of or within entrainment of circadian clock by photoperiod IMP
IMP: Inferred from mutant phenotype
15741322 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
12690040 MGI
acts upstream of or within neuron development IMP
IMP: Inferred from mutant phenotype
15741322 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear receptor subfamily 2 group F member 6

  • COUP transcription factor 3

  • EAR-2

  • V-erbA-related protein 2

  • avian erythroblastic leukemia viral (v-erb-a) oncogene homolog-like 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-147228 NR2F6 modulator-1 Modulator 99.46% Unkown
HY-W649594 NR2F6 modulator-2 Modulator 99.46% Unkown
HY-RS09543 NR2F6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-118912 BMH-9 / Unkown
HY-RS17508 Nr2f6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23965 Nr2f6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nr2f6 NCBI NCBI:2063