1. Gene
  2. CHODL - chondrolectin Gene

CHODL - chondrolectin Gene

Homo sapiens

Also known as MT75; PRED12; C21orf68

Gene ID: 140578 | Gene type: protein coding

About CHODL

Cytogenetic location: 21q21.1 Genomic coordinates (GRCh38): 21:17,917,340-18,267,370 (from NCBI)

This gene has 7 transcripts (splice variants), 200 orthologues and 1 paralogue. Biased expression in testis (RPKM 14.8), spleen (RPKM 3.6) and 5 other tissues.

Summary

This gene encodes a type I membrane protein with a carbohydrate recognition domain characteristic of C-type lectins in its extracellular portion. In other proteins, this domain is involved in endocytosis of glycoproteins and exogenous sugar-bearing pathogens. This protein localizes predominantly to the perinuclear region. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]

CHODL Products(6)

mRNA Protein Name
NM_001204174.2 NP_001191103.1 chondrolectin isoform b
NM_001204175.2 NP_001191104.1 chondrolectin isoform c
NM_001204176.2 NP_001191105.1 chondrolectin isoform c
NM_001204177.2 NP_001191106.1 chondrolectin isoform d
NM_001204178.2 NP_001191107.1 chondrolectin isoform d
NM_024944.3 NP_079220.2 chondrolectin isoform a precursor

CHODL Protein Structure

Lectin_C

Lectin_C: Lectin C-type domain (51 - 179)

  • 0
  • 100
  • 200
  • 273 a.a.
Protein Preferred Names Protein Names

chondrolectin

transmembrane protein MT75

Recombinant CHODL Proteins

Cat. No. Product Name Accession Purity
HY-P77897 CHODL Protein, Human (HEK293, Fc) Q9H9P2 (R22-N216) ≥95%

Related Diseases

Diseases Alias
Enterokinase Deficiency

Enteropeptidase Deficiency

Congenital Enterokinase Deficiency

Congenital Enteropathy Due To Enteropeptidase Deficiency

Deficiency Of Enteropeptidase

ENTKD

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CHODL RGD RGD:1309885
Bos taurus CHODL VGNC VGNC:27308
Mus musculus CHODL MGD MGI:2179069
Canis familiaris CHODL VGNC VGNC:39225
Macaca mulatta CHODL VGNC VGNC:70985
Felis catus CHODL VGNC VGNC:60867
Others CHODL NCBI