CHODL Protein, Human (HEK293, Fc)

CHODL protein contributes to nervous system development, affecting neurite outgrowth and motor axon growth. Interacting with RABGGTB, it plays a crucial role in cellular processes and neural circuit establishment. Investigating CHODL's mechanisms and effects in neurite outgrowth and motor axon growth can offer insights into its role in shaping the developing nervous system. CHODL Protein, Human (HEK293, Fc) is the recombinant human-derived CHODL protein, expressed by HEK293 , with C-hFc labeled tag.

For research use only. We do not sell to patients.
  • Species: Human
  • Source: HEK293
  • Storage:
    Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
  • Biological Activity
  • Technical Parameters
  • Product Properties
  • Documentation
  • Help & FAQs

Biological Activity

Description

CHODL protein contributes to nervous system development, affecting neurite outgrowth and motor axon growth. Interacting with RABGGTB, it plays a crucial role in cellular processes and neural circuit establishment. Investigating CHODL's mechanisms and effects in neurite outgrowth and motor axon growth can offer insights into its role in shaping the developing nervous system. CHODL Protein, Human (HEK293, Fc) is the recombinant human-derived CHODL protein, expressed by HEK293 , with C-hFc labeled tag.

Background

The CHODL protein appears to be involved in the development of the nervous system, particularly in processes such as neurite outgrowth and elongation. Its potential role suggests a contribution to the intricate mechanisms that govern the formation and extension of neuronal projections. Moreover, CHODL may participate in motor axon growth and guidance, indicating a broader influence on the establishment of neural circuits and connectivity. The interaction between CHODL and RABGGTB suggests a molecular partnership that could play a crucial role in mediating the cellular processes associated with CHODL's functions in nervous system development. Further exploration into the specific mechanisms and downstream effects of CHODL in neurite outgrowth, elongation, and motor axon growth could provide valuable insights into its role in shaping the structural and functional aspects of the developing nervous system.

Technical Parameters

  • Species Human
  • Source HEK293
  • Tag C-hFc
  • Accession
  • Gene ID
  • Molecular Construction
    • N-term
    • CHODL (R22-N216)
      Accession # Q9H9P2-1
    • hFc
    • C-term
  • Protein Length

    Extracellular Domain

  • Synonyms

    CHODL; MT75; Prev. C21orf68; FLJ12627; PRED12; Chromosome 21 Open Reading Frame 68; Chondrolectin; Transmembrane Protein MT75

  • AA Sequence

    RRVVSGQKVCFADFKHPCYKMAYFHELSSRVSFQEARLACESEGGVLLSLENEAEQKLIESMLQNLTKPGTGISDGDFWIGLWRNGDGQTSGACPDLYQWSDGSNSQYRNWYTDEPSCGSEKCVVMYHQPTANPGLGGPYLYQWNDDRCNMKHNYICKYEPEINPTAPVEKPYLTNQPGDTHQNVVVTEAGIIPN

  • Predicted Molecular Mass

    48.7 kDa

  • Molecular Weight

    Approximately 65-68 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

  • Glycosylation

    Yes

  • Purity

    ≥ 95%, as determined by Bis-Tris PAGE.

Product Properties

Appearance

Solution

Endotoxin Level

<1 EU/μg, determined by LAL method.

Storage & Stability

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Calculators

Reconstitution Calculator

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

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Desired Reconstitution Concentration Desired Reconstitution Concentration
Dilution Calculator

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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The Specific Activity Calculator Equation
  • Specific Activity (Unit/mg)
  • Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) Specific Activity (Unit/mg)
Unit/mg
= 106 ÷
Biological Activity (ED50) Biological Activity (ED50)
106 ÷
ng/mL
MOQ
Minimum order quantity
100 mg

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