Fabp3 - fatty acid binding protein 3, muscle and heart Gene

Also Known as Mdgi; Fabph1; Fabph4; H-FABP; Fabph-1; Fabph-4

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14077

Summary

Predicted to enable cytoskeletal protein binding activity; fatty acid binding activity; and long-chain fatty acid transporter activity. Involved in several processes, including lipid homeostasis; lipid transport; and positive regulation of long-chain fatty acid import into cell. Acts upstream of or within brown fat cell differentiation and regulation of phosphatidylcholine biosynthetic process. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Human ortholog(s) of this gene implicated in hypertension and type 2 diabetes mellitus. Orthologous to human FABP3 (fatty acid binding protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Fabp3 Products (1)

mRNA Protein Name
NM_010174.2 NP_034304.1 fatty acid-binding protein, heart

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within brown fat cell differentiation IDA
IDA: Inferred from direct assay
28763438 MGI
involved in cholesterol homeostasis IMP
IMP: Inferred from mutant phenotype
15835924 MGI
involved in intracellular lipid transport IMP
IMP: Inferred from mutant phenotype
10224224 MGI
involved in long-chain fatty acid transport IDA
IDA: Inferred from direct assay
15835924 MGI
involved in long-chain fatty acid transport IMP
IMP: Inferred from mutant phenotype
10224224 MGI
involved in phospholipid homeostasis IMP
IMP: Inferred from mutant phenotype
15835924 MGI
involved in positive regulation of long-chain fatty acid import into cell IDA
IDA: Inferred from direct assay
15835924 MGI
involved in positive regulation of long-chain fatty acid import into cell IMP
IMP: Inferred from mutant phenotype
10224224 MGI
involved in regulation of fatty acid oxidation IMP
IMP: Inferred from mutant phenotype
10224224 MGI
acts upstream of or within regulation of phosphatidylcholine biosynthetic process IGI
IGI: Inferred from genetic interaction
15164767 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
23141496 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fatty acid-binding protein, heart

  • fatty acid binding protein heart 1

  • fatty acid binding protein heart 4

  • fatty acid-binding protein 3

  • heart-type fatty acid-binding protein

  • mammary-derived growth inhibitor

Recombinant Fabp3 Proteins

Cat. No. Product Name Accession Purity
HY-P75218 FABP3 Protein, Mouse P11404 (M1-A133) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-P4115 CooP / Phase 2

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-101903 BMS-309403 Inhibitor 99.91% Unkown
HY-101903A BMS-309403 sodium Inhibitor 99.89% Unkown
HY-161702 RO6806051 Inhibitor 99.82% Unkown
HY-163032 FABP4-IN-3 Inhibitor 99.64% Unkown
HY-W040255 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine 99.9% Unkown
HY-148665 FABP-IN-2 Inhibitor 99.78% Unkown
HY-149953 FABP4-IN-2 Inhibitor / Unkown
HY-178471 FABP4/5-IN-6 Inhibitor / Unkown
HY-RS04659 FABP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16971 Fabp3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23414 Fabp3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fabp3 NCBI NCBI:2170