Ttbk2 - tau tubulin kinase 2 Gene
Also Known as TTK; Ttbk; Ttbk1; mKIAA0847; 2610507N02Rik; B930008N24Rik
Species: Mus musculus
Gene Type: protein coding
Gene ID: 140810
Summary
Enables protein serine/threonine kinase activity. Involved in cilium assembly; hindbrain development; and smoothened signaling pathway. Acts upstream of or within several processes, including embryonic brain development; nervous system development; and positive regulation of non-motile cilium assembly. Located in centriole; ciliary basal body; and ciliary transition zone. Is expressed in nervous system. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Orthologous to human TTBK2 (tau tubulin kinase 2). [provided by Alliance of Genome Resources, Apr 2022]
Ttbk2 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001024856.2 | NP_001020027.1 | tau-tubulin kinase 2 isoform 2 |
| NM_001024857.2 | NP_001020028.1 | tau-tubulin kinase 2 isoform 2 |
| NM_080788.3 | NP_542966.2 | tau-tubulin kinase 2 isoform 1 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
tau-tubulin kinase 2 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(9)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-120929 | BI8622 | Inhibitor | 98.16% | Unkown |
| HY-172545 | AMG28 | Inhibitor | 99.74% | Unkown |
| HY-172544 | TTBK1/2-IN-3 | Inhibitor | / | Unkown |
| HY-172542 | TTBK1/2-IN-1 | Inhibitor | / | Unkown |
| HY-172543 | TTBK1/2-IN-2 | Inhibitor | / | Unkown |
| HY-E70871 | TTBK2 Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-RS15194 | TTBK2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS21071 | Ttbk2 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS27588 | Ttbk2 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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