Gart - phosphoribosylglycinamide formyltransferase Gene

Also Known as Gaps; Prgs

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14450

Summary

Enables phosphoribosylamine-glycine Ligase activity. Involved in purine ribonucleoside monophosphate biosynthetic process. Is active in cytosol. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human GART (phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase). [provided by Alliance of Genome Resources, Apr 2022]

Gart Products (2)

mRNA Protein Name
NM_001357351.1 NP_001344280.1 trifunctional purine biosynthetic protein adenosine-3
NM_010256.2 NP_034386.2 trifunctional purine biosynthetic protein adenosine-3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables phosphoribosylamine-glycine ligase activity IDA
IDA: Inferred from direct assay
8299947 MGI
Biological Process GO Annotation Evidence References Source
involved in 'de novo' AMP biosynthetic process IDA
IDA: Inferred from direct assay
8299947 MGI
involved in 'de novo' IMP biosynthetic process IDA
IDA: Inferred from direct assay
8299947 MGI
involved in 'de novo' XMP biosynthetic process IDA
IDA: Inferred from direct assay
8299947 MGI
involved in GMP biosynthetic process IDA
IDA: Inferred from direct assay
8299947 MGI
Cellular Component GO Annotation Evidence References Source
is active in cytosol IDA
IDA: Inferred from direct assay
8299947 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

trifunctional purine biosynthetic protein adenosine-3

  • glycinamide ribonucleotide synthetase

  • glycinamide ribonucleotide synthetase-aminoimidazole ribonucleotide synthetase-glycinamide ribonucleotide formyltransferase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05280 GART Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18934 Gart Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25424 Gart Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gart NCBI NCBI:2618