Hdgf - heparin binding growth factor Gene

Also Known as D3Ertd299e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15191

Summary

Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; cytoskeletal protein binding activity; and growth factor activity. Acts upstream of or within cellular response to interleukin-7 and negative regulation of neuron apoptotic process. Located in extracellular space and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; liver; sensory organ; and telencephalon ventricular layer. Orthologous to human HDGF (heparin binding growth factor). [provided by Alliance of Genome Resources, Apr 2022]

Hdgf Products (14)

mRNA Protein Name
NM_001331051.2 NP_001317980.1 hepatoma-derived growth factor isoform 2
NM_001331052.2 NP_001317981.1 hepatoma-derived growth factor isoform 3
NM_001410032.1 NP_001396961.1 hepatoma-derived growth factor isoform 4
NM_001410033.1 NP_001396962.1 hepatoma-derived growth factor isoform 5
NM_001410034.1 NP_001396963.1 hepatoma-derived growth factor isoform 6
NM_001410035.1 NP_001396964.1 hepatoma-derived growth factor isoform 2
NM_001410036.1 NP_001396965.1 hepatoma-derived growth factor isoform 2
NM_001410037.1 NP_001396966.1 hepatoma-derived growth factor isoform 2
NM_001410038.1 NP_001396967.1 hepatoma-derived growth factor isoform 3
NM_001410039.1 NP_001396968.1 hepatoma-derived growth factor isoform 3
NM_001410040.1 NP_001396969.1 hepatoma-derived growth factor isoform 3
NM_001410041.1 NP_001396970.1 hepatoma-derived growth factor isoform 7
NM_001410042.1 NP_001396971.1 hepatoma-derived growth factor isoform 8
NM_008231.5 NP_032257.3 hepatoma-derived growth factor isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22212508 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to interleukin-7 IDA
IDA: Inferred from direct assay
29581031 MGI
acts upstream of or within negative regulation of neuron apoptotic process IDA
IDA: Inferred from direct assay
15140875 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
15140875 MGI
located in nucleus IDA
IDA: Inferred from direct assay
14572309 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hepatoma-derived growth factor

Hdgf Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Hdgf P51859 q3umu9-1 Mus musculus Q3UMU9-1
IF
22212508
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant Hdgf Proteins

Cat. No. Product Name Accession Purity
HY-P700181AF Animal-Free HDGF Protein, Mouse (His) P51859 (M1-L237) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P700488 HDGF Protein, Mouse (P. pastoris, N-His, C-Myc) P51859 (M1-L237) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06094 HDGF Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17289 Hdgf Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23744 Hdgf Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hdgf NCBI NCBI:3068