HDGF Protein, Mouse (P. pastoris, N-His, C-Myc)
HDGF Protein, a transcriptional repressor, promotes fibroblast mitogenic activity. Existing as a monomer or domain-swapped homodimer, it interacts with nuclear proteins NCL and YBX1/YB1. HDGF Protein, Mouse (P. pastoris, N-His, C-Myc) is the recombinant mouse-derived HDGF protein, expressed by P. pastoris , with C-Myc, N-10*His labeled tag.
- Species: Mouse
- Source: P. pastoris
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
HDGF Protein, a transcriptional repressor, promotes fibroblast mitogenic activity. Existing as a monomer or domain-swapped homodimer, it interacts with nuclear proteins NCL and YBX1/YB1. HDGF Protein, Mouse (P. pastoris, N-His, C-Myc) is the recombinant mouse-derived HDGF protein, expressed by P. pastoris , with C-Myc, N-10*His labeled tag.
Background
HDGF Protein functions as a transcriptional repressor and exhibits mitogenic activity for fibroblasts. This heparin-binding protein can exist as a monomer and as a domain-swapped homodimer. Additionally, it interacts with nuclear proteins NCL and YBX1/YB1.
Technical Parameters
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Species Mouse
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Source P. pastoris
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Tag C-Myc;N-10*His
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Accession
P51859 (M1-L237)
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Molecular Construction
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N-term
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10*His
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HDGF (M1-L237)
Accession # P51859 -
Myc
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C-term
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Protein Length
Full Length
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Synonyms
HDGF; Hepatoma-Derived Growth Factor; Heparin Binding Growth Factor; Hepatoma-Derived Growth Factor (High-Mobility Group Protein 1-Like); HMG1L2; High-Mobility Group Protein 1-Like; Epididymis Secretory Sperm Binding Protein; Hepatoma-Derived Growth Facto
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AA Sequence
MSRSNRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCAAEPEVEPEAHEGDGDKKGSAEGSSDEEGKLVIDEPAKEKNEKGTLKRRAGDVLEDSPKRPKESGDHEEEDKEIAALEGERPLPVEVEKNSTPSEPDSGQGPPAEEEEGEEEAAKEEAEAQGVRDHESL
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Predicted Molecular Mass
30.3 kDa
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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