Hpca - hippocalcin Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15444

Summary

Predicted to enable several functions, including actin binding activity; calcium ion binding activity; and identical protein binding activity. Acts upstream of or within inner ear development. Predicted to be located in several cellular components, including dendrite; neuronal cell body membrane; and perikaryon. Predicted to be extrinsic component of membrane. Is expressed in ganglia and telencephalon. Human ortholog(s) of this gene implicated in torsion dystonia 2. Orthologous to human HPCA (hippocalcin). [provided by Alliance of Genome Resources, Apr 2022]

Hpca Products (4)

mRNA Protein Name
NM_001130419.2 NP_001123891.1 neuron-specific calcium-binding protein hippocalcin
NM_001286081.1 NP_001273010.1 neuron-specific calcium-binding protein hippocalcin
NM_001286083.1 NP_001273012.1 neuron-specific calcium-binding protein hippocalcin
NM_010471.4 NP_034601.1 neuron-specific calcium-binding protein hippocalcin

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
14739275 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within inner ear development IDA
IDA: Inferred from direct assay
21795542 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuron-specific calcium-binding protein hippocalcin

Hpca Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Hpca P84075 Kcnma1 Mus musculus Q08460
Anti Bait CoIP
19423573
Intra
Hpca P84075 Kcnma1 Mus musculus Q08460
Confocal
19423573
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01791 CACNA1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06333 HPCA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17810 Hpca Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21232 Cacna1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24278 Hpca Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hpca NCBI NCBI:3208