Ifna1 - interferon alpha 1 Gene

Also Known as Ifa1; If1ai14

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15962

Summary

Enables cytokine activity. Involved in regulation of defense response to virus by host and type I interferon signaling pathway. Acts upstream of or within defense response to Other organism and lymphocyte activation involved in immune response. Located in extracellular space. Is expressed in embryo. Human ortholog(s) of this gene implicated in Crimean-Congo hemorrhagic fever; common cold; hepatitis B; liver disease (multiple); and sarcoidosis. Orthologous to several human genes including IFNA10 (interferon alpha 10); IFNA14 (interferon alpha 14); and IFNA16 (interferon alpha 16). [provided by Alliance of Genome Resources, Apr 2022]

Ifna1 Products (1)

mRNA Protein Name
NM_010502.2 NP_034632.2 interferon alpha-1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cytokine activity IDA
IDA: Inferred from direct assay
15240719 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within T cell activation involved in immune response IDA
IDA: Inferred from direct assay
19130550 MGI
acts upstream of or within defense response to bacterium IDA
IDA: Inferred from direct assay
15240719 MGI
acts upstream of or within defense response to virus IDA
IDA: Inferred from direct assay
19130550 MGI
acts upstream of or within natural killer cell activation involved in immune response IDA
IDA: Inferred from direct assay
19130550 MGI
involved in regulation of defense response to virus by host IDA
IDA: Inferred from direct assay
24784232 MGI
involved in type I interferon-mediated signaling pathway IDA
IDA: Inferred from direct assay
24784232 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
19130550 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interferon alpha-1

  • IFN-alpha-1

  • interferon 1ai14

  • interferon alpha family gene 1

Recombinant Ifna1 Proteins

Cat. No. Product Name Accession Purity
HY-P74866 IFN-alpha 1/IFNA1 Protein, Mouse (P.pastoris, His) P01572 (C24-K189) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P700183AF Animal-Free IFN alpha 1/IFNA1 Protein, Mouse (His) P01572 (C24-K189) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P701053 IFN-alpha 1/IFNA1 Protein, Mouse (HEK293, hFc) P01572 (C24-K189) ≥ 95%, as determined by reducing Tris-Bis PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06570 IFNA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17552 Ifna1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P99611 Faralimomab Inhibitor 95.00% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ifna1 NCBI NCBI:3439