Kif2a - kinesin family member 2A Gene

Also Known as Kif2; Kns2; M-kinesin; C530030B14Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16563

Summary

Predicted to enable several functions, including ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in microtubule-based movement; mitotic spindle assembly; and regulation of cell migration. Predicted to act upstream of or within cell differentiation; cell division; and nervous system development. Located in sperm principal piece. Is expressed in central nervous system and dorsal root ganglion. Human ortholog(s) of this gene implicated in complex cortical dysplasia with Other brain malformations 3. Orthologous to human KIF2A (Kinesin family member 2A). [provided by Alliance of Genome Resources, Apr 2022]

Kif2a Products (8)

mRNA Protein Name
NM_001145779.1 NP_001139251.1 kinesin-like protein KIF2A isoform 2
NM_001374727.1 NP_001361656.1 kinesin-like protein KIF2A isoform 3
NM_001378936.1 NP_001365865.1 kinesin-like protein KIF2A isoform 4
NM_001378937.1 NP_001365866.1 kinesin-like protein KIF2A isoform 5
NM_001378938.1 NP_001365867.1 kinesin-like protein KIF2A isoform 6
NM_001378939.1 NP_001365868.1 kinesin-like protein KIF2A isoform 7
NM_001378940.1 NP_001365869.1 kinesin-like protein KIF2A isoform 8
NM_008442.2 NP_032468.2 kinesin-like protein KIF2A isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in dendritic transport IDA
IDA: Inferred from direct assay
36733270 MGI
involved in dendritic transport IMP
IMP: Inferred from mutant phenotype
36733270 MGI
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
36733270 MGI
is active in GABA-ergic synapse IMP
IMP: Inferred from mutant phenotype
36733270 MGI
located in sperm principal piece IDA
IDA: Inferred from direct assay
24339785 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kinesin-like protein KIF2A

  • kinesin heavy chain member 2

  • kinesin-2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-173522 KIF2C-IN-1 98.08% Unkown
HY-177898 DHTP Inhibitor 99.42% Unkown
HY-RS07282 KIF2A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20433 Kif2a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26942 Kif2a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kif2a NCBI NCBI:3796