Rac3 - Rac family small GTPase 3 Gene

Also Known as Rac1B

Species: Mus musculus

Gene Type: protein coding
Gene ID: 170758

Summary

Predicted to enable several functions, including GTP binding activity; GTPase activity; and calcium-dependent protein binding activity. Acts upstream of or within several processes, including GABAergic synaptic transmission; neuron development; and regulation of neuron maturation. Predicted to be located in several cellular components, including growth cone; neuronal cell body; and perinuclear region of cytoplasm. Predicted to be part of filamentous actin. Predicted to be active in several cellular components, including cell cortex; cytoplasmic vesicle; and neuron projection. Is expressed in brain and genitourinary system. Orthologous to human RAC3 (Rac family small GTPase 3). [provided by Alliance of Genome Resources, Apr 2022]

Rac3 Products (1)

mRNA Protein Name
NM_133223.4 NP_573486.1 ras-related C3 botulinum toxin substrate 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15102471 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cerebral cortex GABAergic interneuron development IGI
IGI: Inferred from genetic interaction
23258346 MGI
acts upstream of or within homeostasis of number of cells within a tissue IGI
IGI: Inferred from genetic interaction
23258346 MGI
acts upstream of or within neuromuscular process IMP
IMP: Inferred from mutant phenotype
15964829 MGI
acts upstream of or within neuromuscular process controlling balance IMP
IMP: Inferred from mutant phenotype
15964829 MGI
acts upstream of or within neuron projection development IDA
IDA: Inferred from direct assay
16525025 MGI
acts upstream of or within regulation of cell morphogenesis IGI
IGI: Inferred from genetic interaction
23258346 MGI
acts upstream of or within regulation of neuron maturation IGI
IGI: Inferred from genetic interaction
23258346 MGI
involved in regulation of postsynapse assembly IDA
IDA: Inferred from direct assay
31369617 MGI
involved in regulation of postsynapse assembly IMP
IMP: Inferred from mutant phenotype
31369617 MGI
acts upstream of or within synaptic transmission, GABAergic IGI
IGI: Inferred from genetic interaction
23258346 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
31369617 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
31369617 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
31369617 MGI
is active in postsynapse IMP
IMP: Inferred from mutant phenotype
31369617 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-related C3 botulinum toxin substrate 3

  • RAS-related C3 botulinum substrate 3

  • p21-Rac3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (14)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-16659 EHT 1864 Inhibitor 99.85% Unkown
HY-12810 EHop-016 Inhibitor 99.38% Unkown
HY-113801 N-(3-Oxooctanoyl)-DL-homoserine lactone 99.69% Unkown
HY-132404S (rac)-3-O-Methyl DOPA-d3 97.0% Unkown
HY-RS09091 NCOA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-100841 (Rac)-3-Hydroxyphenylglycine Control 99.14% Unkown
HY-136345 (Rac)-3′-Hydroxy simvastatin 99.71% Unkown
HY-167811 1,2-Dipalmitoyl-sn-glycero-3-[phospho-rac-(3-lysyl(1-glycerol))] hydrochloride / Unkown
HY-RS11593 RAC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W653885 rac 3,4-Dihydroxymandelic Acid-d3 / Unkown
HY-RS20451 Ncoa3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21413 Rac3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27932 Rac3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W779204 rac-3-Hexadecanamido-2-methoxypropan-1-ol phosphocholine hydrate / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rac3 NCBI NCBI:5881