Mak - male germ cell-associated kinase Gene

Also Known as A930010O05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17152

Summary

Enables protein kinase activity. Acts upstream of or within negative regulation of non-motile cilium assembly and photoreceptor cell maintenance. Located in several cellular components, including axoneme; ciliary tip; and photoreceptor cell cilium. Is expressed in several structures, including brain; nasal cavity epithelium; neural retina; respiratory system; and testis. Human ortholog(s) of this gene implicated in retinitis pigmentosa 62. Orthologous to human MAK (male germ cell associated kinase). [provided by Alliance of Genome Resources, Apr 2022]

Mak Products (3)

mRNA Protein Name
NM_001145802.1 NP_001139274.1 serine/threonine-protein kinase MAK isoform 3
NM_001145803.1 NP_001139275.1 serine/threonine-protein kinase MAK isoform 1
NM_008547.2 NP_032573.2 serine/threonine-protein kinase MAK isoform 2
Protein Preferred Names Protein Names

serine/threonine-protein kinase MAK

  • protein kinase RCK

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-103663 MAK683 Inhibitor 99.02% Phase 1

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-130815A MAK683-C2-acid hydrochloride Inhibitor 99.60% Unkown
HY-130815 MAK683-CH2CH2COOH Inhibitor / Unkown
HY-103663A MAK683 hydrochloride Inhibitor / Unkown
HY-RS00631 ALPK3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07989 MAK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07990 MAK16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17873 Mak Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24342 Mak Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P99425 Afelimomab 99.34% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mak NCBI NCBI:4117