1. Epigenetics
  2. Epigenetic Reader Domain

EED inhibitor-1 

Cat. No.: HY-103663 Purity: 98.05%
Handling Instructions

EED inhibitor-1 is an EED inhibitor extracted from patent US20160176882 A1, compound example 2; has IC50s of 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay.

For research use only. We do not sell to patients.

EED inhibitor-1 Chemical Structure

EED inhibitor-1 Chemical Structure

CAS No. : 1951408-58-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 290 In-stock
Estimated Time of Arrival: December 31
5 mg USD 264 In-stock
Estimated Time of Arrival: December 31
10 mg USD 444 In-stock
Estimated Time of Arrival: December 31
25 mg USD 888 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1320 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

EED inhibitor-1 is an EED inhibitor extracted from patent US20160176882 A1, compound example 2; has IC50s of 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay.

IC50 & Target

IC50: 59 nM (EED Alphascreen), 89 nM (LC-MS), 26 nM (ELISA)[1]

In Vitro

EED inhibitor-1 has antiproliferative activities in B cell lymphoma cell KARPAS422 after 14 days of treatment with an IC50 of 30 nM[1].

Solvent & Solubility
In Vitro: 

DMSO : ≥ 30 mg/mL (79.70 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6568 mL 13.2841 mL 26.5682 mL
5 mM 0.5314 mL 2.6568 mL 5.3136 mL
10 mM 0.2657 mL 1.3284 mL 2.6568 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

376.39

Formula

C₂₀H₁₇FN₆O

CAS No.

1951408-58-4

SMILES

CC1=NC=CC=C1C2=CN=C(NCC3=C4CCOC4=CC=C3F)N5C2=NN=C5

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
EED inhibitor-1
Cat. No.:
HY-103663
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EED inhibitor-1

Cat. No.: HY-103663