Mrc1 - mannose receptor, C type 1 Gene

Also Known as MR; CD206

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17533

Summary

Enables mannose binding activity and transmembrane signaling receptor activity. Acts upstream of or within cellular response to interferon-gamma; cellular response to interleukin-4; and cellular response to lipopolysaccharide. Located in cell surface. Is expressed in several structures, including hemolymphoid system; intestine; liver; lung; and yolk sac. Orthologous to human MRC1 (Mannose Receptor C-type 1). [provided by Alliance of Genome Resources, Apr 2022]

Mrc1 Products (1)

mRNA Protein Name
NM_008625.2 NP_032651.2 macrophage mannose receptor 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables D-mannose binding IDA
IDA: Inferred from direct assay
1421407 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
32766577 MGI
enables transmembrane signaling receptor activity IDA
IDA: Inferred from direct assay
1421407 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to interleukin-4 IDA
IDA: Inferred from direct assay
22832163 MGI
acts upstream of or within cellular response to lipopolysaccharide IDA
IDA: Inferred from direct assay
22832163 MGI
acts upstream of or within cellular response to type II interferon IDA
IDA: Inferred from direct assay
22832163 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
1421407 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

macrophage mannose receptor 1

  • MMR

Mrc1 Antibodies

Cat. No. Product Name Application Reactivity
HY-P83714M Rat Anti-Mouse CD206 Antibody (APC) FC Mouse

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P10894 mUNO 97.50% Unkown
HY-107509 LY2389575 hydrochloride Modulator 99.93% Unkown
HY-169859 EP4 receptor antagonist 7 Antagonist 99.9% Unkown
HY-P11462 UNO peptide Ligand / Unkown
HY-RS08641 MRC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19618 Mrc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26113 Mrc1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mrc1 NCBI NCBI:4360