Msn - moesin Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17698

Summary

Predicted to enable several functions, including actin binding activity; double-stranded RNA binding activity; and protein kinase binding activity. Acts upstream of or within positive regulation of podosome assembly. Located in several cellular components, including basolateral plasma membrane; microvillus; and uropod. Is expressed in several structures, including cardiovascular system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in immunodeficiency 50. Orthologous to human MSN (moesin). [provided by Alliance of Genome Resources, Apr 2022]

Msn Products (1)

mRNA Protein Name
NM_010833.2 NP_034963.2 moesin

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
9472040 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of podosome assembly IDA
IDA: Inferred from direct assay
24127566 MGI
Cellular Component GO Annotation Evidence References Source
located in apical part of cell IDA
IDA: Inferred from direct assay
9890997 MGI
located in apical plasma membrane IDA
IDA: Inferred from direct assay
14625387 MGI
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
14625387 MGI
located in microvillus IDA
IDA: Inferred from direct assay
9472040 MGI
located in uropod IDA
IDA: Inferred from direct assay
11728336 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

moesin

  • membrane-organizing extension spike protein

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P1386 D15 Inhibitor 99.02% Unkown

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-12646 Rhosin hydrochloride 99.94% Unkown
HY-12646A Rhosin 98.74% Unkown
HY-120079 MSN-125 Inhibitor 99.67% Unkown
HY-118948 MSN-50 Inhibitor 98.09% Unkown
HY-140678 mPEG10000-amine 98.0% Unkown
HY-RS18452 Msn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-149410 MSN8C Inhibitor / Unkown
HY-174929 DBCO-PEG3400-Amine / Unkown
HY-174929A DBCO-PEG5000-Amine / Unkown
HY-RS08723 MSN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24933 Msn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Msn NCBI NCBI:4478