Nid1 - nidogen 1 Gene

Also Known as Nid; entactin; nidogen-1; A630025O17; entactin-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18073

Summary

Enables Collagen binding activity and laminin-1 binding activity. Acts upstream of or within cell-matrix adhesion; glomerular basement membrane development; and positive regulation of cell-substrate adhesion. Located in basement membrane. Is expressed in several structures, including alimentary system; blastocyst; eye; genitourinary system; and nervous system. Orthologous to human NID1 (nidogen 1). [provided by Alliance of Genome Resources, Apr 2022]

Nid1 Products (1)

mRNA Protein Name
NM_010917.3 NP_035047.2 nidogen-1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables collagen binding IDA
IDA: Inferred from direct assay
17517882 MGI
enables extracellular matrix binding IDA
IDA: Inferred from direct assay
18757743 MGI
enables laminin-1 binding IDA
IDA: Inferred from direct assay
17517882 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
8995276 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cell-matrix adhesion IDA
IDA: Inferred from direct assay
12243745 MGI
acts upstream of or within extracellular matrix organization IDA
IDA: Inferred from direct assay
18757743 MGI
acts upstream of or within glomerular basement membrane development IMP
IMP: Inferred from mutant phenotype
14566019 MGI
acts upstream of or within positive regulation of cell-substrate adhesion IDA
IDA: Inferred from direct assay
18757743 MGI
Cellular Component GO Annotation Evidence References Source
located in basement membrane IDA
IDA: Inferred from direct assay
7670489 MGI
located in basement membrane IPI
IPI: Inferred from physical interaction
12243745 MGI
located in cell periphery IDA
IDA: Inferred from direct assay
19295126 MGI
located in extracellular matrix IDA
IDA: Inferred from direct assay
16618944 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nidogen-1

  • NID-1

  • Nidogen precursor (Entactin)

  • entactin 1

Nid1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Nid1 P10493 Lamc1 Mus musculus P02468
DLS
23948589
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant Nid1 Proteins

Cat. No. Product Name Accession Purity
HY-P71763 Nidogen-1 Protein, Mouse (P.pastoris, His) P10493 (S428-A665) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09294 NID1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18778 Nid1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25267 Nid1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nid1 NCBI NCBI:4811