Ccl21a - chemokine (C-C motif) ligand 21A (serine) Gene

Also Known as ALP; SLC; plt; CKb9; Tca4; 6Ckine; Gm1987; Scya21; 6CKBAC2; SCYA21a; Scya21b

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18829

Summary

Enables CCR7 Chemokine Receptor binding activity and chemokine activity. Involved in several processes, including dendritic cell dendrite assembly; negative regulation of dendritic cell dendrite assembly; and positive regulation of T cell chemotaxis. Acts upstream of or within induction of positive chemotaxis and lymph node development. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in branchial arch; hemolymphoid system; lymph sac; renal vasculature; and trunk. Orthologous to human CCL21 (C-C motif chemokine ligand 21). [provided by Alliance of Genome Resources, Apr 2022]

Ccl21a Products (2)

mRNA Protein Name
NM_011124.4 NP_035254.1 C-C motif chemokine 21a precursor
NM_011124.4 NP_035254.1 C-C motif chemokine 21a precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Referencias Source
enables CCR7 chemokine receptor binding IPI
IPI: Inferred from physical interaction
9507024 MGI
enables chemokine activity IDA
IDA: Inferred from direct assay
12200351 MGI
enables chemokine activity IMP
IMP: Inferred from mutant phenotype
27400149 MGI
Biological Process GO Annotation Evidence Referencias Source
involved in T cell costimulation IDA
IDA: Inferred from direct assay
15845453 MGI
involved in cell maturation IDA
IDA: Inferred from direct assay
15845453 MGI
involved in cellular response to chemokine IMP
IMP: Inferred from mutant phenotype
27400149 MGI
involved in chemokine (C-C motif) ligand 21 signaling pathway IMP
IMP: Inferred from mutant phenotype
27400149 MGI
involved in dendritic cell chemotaxis IDA
IDA: Inferred from direct assay
12200351 MGI
involved in dendritic cell dendrite assembly IDA
IDA: Inferred from direct assay
12200351 MGI
involved in immunological synapse formation IDA
IDA: Inferred from direct assay
15845453 MGI
acts upstream of or within induction of positive chemotaxis IDA
IDA: Inferred from direct assay
9548511 MGI
acts upstream of or within lymph node development IMP
IMP: Inferred from mutant phenotype
12732660 MGI
involved in negative regulation of dendritic cell dendrite assembly IDA
IDA: Inferred from direct assay
12200351 MGI
involved in positive regulation of T cell chemotaxis IMP
IMP: Inferred from mutant phenotype
27400149 MGI
involved in positive regulation of chemotaxis IDA
IDA: Inferred from direct assay
9507024 MGI
involved in positive regulation of dendritic cell antigen processing and presentation IDA
IDA: Inferred from direct assay
15845453 MGI
involved in positive regulation of glycoprotein biosynthetic process IDA
IDA: Inferred from direct assay
15845453 MGI
involved in positive regulation of receptor-mediated endocytosis IDA
IDA: Inferred from direct assay
12609829 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

C-C motif chemokine 21a

  • CC chemokine 6Ckine-ser

  • CCL21-Ser

  • beta-chemokine exodus-2

  • exodus-2

  • small inducible cytokine A21a

  • thymus-derived chemotactic agent 4

Recombinant Ccl21a Proteins

Referencia número Nombre del producto Accession Pureza
HY-P72756 6Ckine/CCL21A Protein, Mouse P84444 (S24-G133) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P75545 6Ckine/CCL21A Protein, Mouse (sf9, His) P84444 (S24-G133) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P75546 6Ckine/CCL21A Protein, Mouse (sf9) P84444 (S24-G133) ≥ 95%, as determined by reducing SDS-PAGE.