Prrx1 - paired related homeobox 1 Gene

Also Known as K-2; Pmx; Pmx1; Prx1; mHox; MHox1; A230024N07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18933

Summary

Enables DNA-binding transcription factor activity, RNA polymerase II-specific; HMG box domain binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including embryonic morphogenesis; neuronal stem cell population maintenance; and positive regulation of smoothened signaling pathway. Located in nucleus. Is expressed in several structures, including brain; cardiovascular system; embryo mesenchyme; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in agnathia-otocephaly complex. Orthologous to human PRRX1 (paired related homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Prrx1 Products (6)

mRNA Protein Name
NM_001025570.1 NP_001020741.1 paired mesoderm homeobox protein 1 isoform c
NM_011127.2 NP_035257.1 paired mesoderm homeobox protein 1 isoform a
NM_175686.3 NP_783617.2 paired mesoderm homeobox protein 1 isoform b
NM_001025570.1 NP_001020741.1 paired mesoderm homeobox protein 1 isoform c
NM_011127.2 NP_035257.1 paired mesoderm homeobox protein 1 isoform a
NM_175686.3 NP_783617.2 paired mesoderm homeobox protein 1 isoform b
Protein Preferred Names Protein Names

paired mesoderm homeobox protein 1

  • homeobox protein K-2

  • homeobox protein mHox

  • paired-related homeobox protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11243 PRRX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20468 Prrx1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26977 Prrx1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prrx1 NCBI NCBI:5396