Ptch2 - patched 2 Gene

Also Known as ptc2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19207

Summary

This gene encodes a member of the patched family of transmembrane Receptor Proteins. The encoded protein may be a functional receptor for the morphogen sonic Hedgehog (Shh) and is reportedly involved in limb and skin development. Homozygous mutant mice for this gene exhibit hair loss and epidermal hyperplasia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

Ptch2 Products (2)

mRNA Protein Name
NM_001312903.1 NP_001299832.1 protein patched homolog 2 isoform 2
NM_008958.3 NP_032984.1 protein patched homolog 2 isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within cell fate determination IGI
IGI: Inferred from genetic interaction
24492243 MGI
acts upstream of or within epidermal cell fate specification IGI
IGI: Inferred from genetic interaction
24492243 MGI
acts upstream of or within epidermis development IMP
IMP: Inferred from mutant phenotype
16914743 MGI
acts upstream of or within hair cycle IMP
IMP: Inferred from mutant phenotype
16914743 MGI
acts upstream of or within positive regulation of epidermal cell differentiation IGI
IGI: Inferred from genetic interaction
24492243 MGI
acts upstream of or within skin development IMP
IMP: Inferred from mutant phenotype
16914743 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein patched homolog 2

  • patched homolog 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11357 PTCH2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22751 Ptch2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25164 Ptch1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29265 Ptch2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptch2 NCBI NCBI:8643