Ptgds - prostaglandin D2 synthase (brain) Gene

Also Known as PGD2; PGDS; 21kDa; PGDS2; Ptgs3; L-PGDS

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19215

Summary

Enables prostaglandin-D synthase activity and retinoid binding activity. Involved in prostaglandin biosynthetic process and regulation of circadian sleep/wake cycle, sleep. Acts upstream of or within negative regulation of male germ cell proliferation. Located in extracellular region. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in carotid artery disease. Orthologous to human PTGDS (prostaglandin D2 synthase). [provided by Alliance of Genome Resources, Apr 2022]

Ptgds Products (1)

mRNA Protein Name
NM_008963.3 NP_032989.2 prostaglandin-H2 D-isomerase precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables prostaglandin-D synthase activity IDA
IDA: Inferred from direct assay
17715133 MGI
enables retinoid binding IDA
IDA: Inferred from direct assay
17715133 MGI
Biological Process GO Annotation Evidence References Source
involved in gene expression IDA
IDA: Inferred from direct assay
26025376 MGI
involved in gene expression IMP
IMP: Inferred from mutant phenotype
26025376 MGI
acts upstream of or within negative regulation of male germ cell proliferation IGI
IGI: Inferred from genetic interaction
25142465 MGI
involved in prostaglandin biosynthetic process IDA
IDA: Inferred from direct assay
17715133 MGI
involved in regulation of circadian sleep/wake cycle, sleep IDA
IDA: Inferred from direct assay
10781097 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular region IDA
IDA: Inferred from direct assay
8922532 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

prostaglandin-H2 D-isomerase

  • PGD2 synthase

  • glutathione-independent PGD synthase

  • glutathione-independent PGD synthetase

  • lipocalin-type prostaglandin-D synthase

  • prostaglandin D2 synthase (21 kDa, brain)

  • prostaglandin-D2 synthase

Recombinant Ptgds Proteins

Cat. No. Product Name Accession Purity
HY-P73710 PGD2 Synthase/PTGDS Protein, Mouse (HEK293, His) NP_032989.2 (Q25-E189) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11374 PTGDS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18401 Ptgds Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24882 Ptgds Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptgds NCBI NCBI:5730