Pth1r - parathyroid hormone 1 receptor Gene

Also Known as PPR; Pthr; Pthr1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19228

Summary

Enables parathyroid hormone receptor activity. Acts upstream of or within several processes, including G protein-coupled receptor signaling pathway; bone resorption; and osteoblast development. Predicted to be located in several cellular components, including apical plasma membrane; basolateral plasma membrane; and brush border membrane. Predicted to be integral component of plasma membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including extraembryonic component; integumental system; limb; lung; and skeleton. Human ortholog(s) of this gene implicated in Eiken syndrome; Jansen's metaphyseal chondrodysplasia; chondrodysplasia Blomstrand type; osteochondrodysplasia; and primary failure of tooth eruption. Orthologous to human PTH1R (parathyroid hormone 1 receptor). [provided by Alliance of Genome Resources, Apr 2022]

Pth1r Products (3)

mRNA Protein Name
NM_001083935.1 NP_001077404.1 parathyroid hormone/parathyroid hormone-related peptide receptor precursor
NM_001083936.1 NP_001077405.1 parathyroid hormone/parathyroid hormone-related peptide receptor precursor
NM_011199.2 NP_035329.2 parathyroid hormone/parathyroid hormone-related peptide receptor precursor
Protein Preferred Names Protein Names

parathyroid hormone/parathyroid hormone-related peptide receptor

  • PTH-related peptide receptor

  • PTH/PTHr receptor

  • PTH/PTHrP receptor

  • PTH/PTHrP type I receptor

  • PTH1 receptor

  • parathyroid hormone receptor 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-P4385 (Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) Antagonist 99.77% Unkown
HY-P4821 pTH (1-34) amide (human) Agonist 99.78% Unkown
HY-176943 PTH1R agonist 1 Agonist / Unkown
HY-176945 PTH1R agonist 3 Agonist / Unkown
HY-120398 CH5447240 Agonist / Unkown
HY-186200 PTHR1 antagonist 1 Antagonist / Unkown
HY-176944 PTH1R agonist 2 Agonist / Unkown
HY-113918 SW-106 Antagonist / Unkown
HY-131206 DS37571084 Antagonist / Unkown
HY-179356 Octadecyl β-D-glucopyranosiduronic acid Activator / Unkown
HY-176946 PTH1R agonist 4 Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pth1r NCBI NCBI:5745