Nrbp1 - nuclear receptor binding protein 1 Gene

Also Known as Nrbp; B230344L17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 192292

Summary

Enables protein homodimerization activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and intracellular signal transduction. Located in perinuclear region of cytoplasm. Is expressed in cap mesenchyme; ovary; and renal interstitium. Orthologous to human NRBP1 (nuclear receptor binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Nrbp1 Products (2)

mRNA Protein Name
NM_001347326.1 NP_001334255.1 nuclear receptor-binding protein isoform 1
NM_147201.2 NP_671734.1 nuclear receptor-binding protein isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
NOT enables ATP binding IDA
IDA: Inferred from direct assay
12176995 MGI
enables identical protein binding IPI
IPI: Inferred from physical interaction
12176995 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12176995 MGI
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
12176995 MGI
NOT enables protein kinase activity IDA
IDA: Inferred from direct assay
12176995 MGI
Biological Process GO Annotation Evidence References Source
involved in epithelial cell differentiation IMP
IMP: Inferred from mutant phenotype
22510880 MGI
involved in epithelial cell proliferation IMP
IMP: Inferred from mutant phenotype
22510880 MGI
involved in in utero embryonic development IMP
IMP: Inferred from mutant phenotype
22510880 MGI
Cellular Component GO Annotation Evidence References Source
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
12176995 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear receptor-binding protein

  • HLS7-interacting protein kinase

  • MLF1 adapter molecule

Nrbp1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Nrbp1 Q99J45 Mlf1 Mus musculus Q9QWV4
Y2H
12176995
Intra
Nrbp1 Q99J45 Nrbp1 Mus musculus Q99J45
Y2H
12176995
Intra
Nrbp1 Q99J45 MLF1 Homo sapiens P58340
Y2H
12176995
Intra
Nrbp1 Q99J45 Nrbp1 Mus musculus Q99J45
Anti Tag CoIP
12176995
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09562 NRBP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nrbp1 NCBI NCBI:29959