Ptx3 - pentraxin related gene Gene

Also Known as TSG-14

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19288

Summary

Enables (1->3)-beta-D-glucan binding activity. Acts upstream of or within several processes, including opsonization; ovarian cumulus expansion; and positive regulation of nitric oxide biosynthetic process. Located in extracellular matrix. Is expressed in cochlea; cochlea epithelium; inner ear vestibular component; organ of Corti; and stria vascularis. Human ortholog(s) of this gene implicated in cystic fibrosis and invasive aspergillosis. Orthologous to human PTX3 (pentraxin 3). [provided by Alliance of Genome Resources, Apr 2022]

Ptx3 Products (1)

mRNA Protein Name
NM_008987.3 NP_033013.3 pentraxin-related protein PTX3 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables (1->3)-beta-D-glucan binding IMP
IMP: Inferred from mutant phenotype
14726497 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
17675295 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within extracellular matrix organization IDA
IDA: Inferred from direct assay
17675295 MGI
acts upstream of or within extracellular matrix organization IMP
IMP: Inferred from mutant phenotype
17675295 MGI
acts upstream of or within opsonization IMP
IMP: Inferred from mutant phenotype
14726497 MGI
acts upstream of or within ovarian cumulus expansion IDA
IDA: Inferred from direct assay
17675295 MGI
acts upstream of or within ovarian cumulus expansion IMP
IMP: Inferred from mutant phenotype
17675295 MGI
acts upstream of or within positive regulation of nitric oxide biosynthetic process IMP
IMP: Inferred from mutant phenotype
14726497 MGI
acts upstream of or within positive regulation of phagocytosis IMP
IMP: Inferred from mutant phenotype
14726497 MGI
acts upstream of or within response to yeast IMP
IMP: Inferred from mutant phenotype
14726497 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular matrix IDA
IDA: Inferred from direct assay
17675295 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pentraxin-related protein PTX3

  • pentaxin related

  • pentaxin-related protein PTX3

  • pentraxin 3

  • tumor necrosis factor-inducible gene 14 protein

Recombinant Ptx3 Proteins

Cat. No. Product Name Accession Purity
HY-P71246 PTX3 Protein, Mouse (HEK293, His) P48759 (E18-S381) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10583 PITX3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11457 PTX3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17750 Ptx3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24217 Ptx3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptx3 NCBI NCBI:5806