Rab34 - RAB34, member RAS oncogene family Gene

Also Known as Rah; Narr; Rah1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19376

Summary

Enables GTPase activity and guanyl nucleotide binding activity. Involved in several processes, including Golgi to plasma membrane protein transport; phagosome-lysosome fusion; and positive regulation of protein localization to phagocytic vesicle. Acts upstream of or within endocytosis. Located in Golgi apparatus; endosome; and ruffle. Colocalizes with phagocytic vesicle. Is expressed in several structures, including adrenal gland; alimentary system; brain; genitourinary system; and respiratory system. Orthologous to human RAB34 (RAB34, member Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Rab34 Products (2)

mRNA Protein Name
NM_001159482.1 NP_001152954.1 ras-related protein Rab-34
NM_033475.3 NP_258436.2 ras-related protein Rab-34

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTPase activity IDA
IDA: Inferred from direct assay
12446704 MGI
enables guanyl nucleotide binding IDA
IDA: Inferred from direct assay
12446704 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
22275436 MGI
Biological Process GO Annotation Evidence References Source
involved in Golgi to plasma membrane protein transport IGI
IGI: Inferred from genetic interaction
17881736 MGI
involved in cytosolic ciliogenesis IMP
IMP: Inferred from mutant phenotype
33989524 MGI
acts upstream of or within endocytosis IDA
IDA: Inferred from direct assay
12446704 MGI
involved in lysosomal transport IDA
IDA: Inferred from direct assay
23197834 MGI
involved in phagosome-lysosome fusion IMP
IMP: Inferred from mutant phenotype
23197834 MGI
involved in positive regulation of defense response to bacterium IDA
IDA: Inferred from direct assay
23197834 MGI
involved in positive regulation of protein localization to phagocytic vesicle IMP
IMP: Inferred from mutant phenotype
23197834 MGI
involved in positive regulation of smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
29290584 MGI
Cellular Component GO Annotation Evidence References Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
23197834 MGI
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
23197834 MGI
located in early endosome IDA
IDA: Inferred from direct assay
12446704 MGI
located in late endosome IDA
IDA: Inferred from direct assay
23197834 MGI
colocalizes with phagocytic vesicle IDA
IDA: Inferred from direct assay
23197834 MGI
located in ruffle IDA
IDA: Inferred from direct assay
12446704 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-related protein Rab-34

  • RAB34, member of RAS oncogene family

  • rab-39

  • ras-related homolog

  • ras-related protein Rab-39

  • ras-related protein Rah

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11548 RAB34 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22761 Rab34 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29275 Rab34 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rab34 NCBI NCBI:83871