Sar1a - secretion associated Ras related GTPase 1A Gene

Also Known as Sara; Sara1; 1600019H17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20224

Summary

Predicted to enable GTPase activity. Acts upstream of or within negative regulation of cargo loading into COPII-coated vesicle and vesicle-mediated transport. Located in Golgi apparatus and sarcoplasmic reticulum. Is expressed in several structures, including genitourinary system; liver; nervous system; retina nuclear layer; and skeletal musculature. Orthologous to human SAR1A (secretion associated Ras related GTPase 1A). [provided by Alliance of Genome Resources, Apr 2022]

Sar1a Products (15)

mRNA Protein Name
NM_001358487.2 NP_001345416.1 GTP-binding protein SAR1a isoform 1
NM_001358488.2 NP_001345417.1 GTP-binding protein SAR1a isoform 1
NM_001406329.1 NP_001393258.1 GTP-binding protein SAR1a isoform 1
NM_001406330.1 NP_001393259.1 GTP-binding protein SAR1a isoform 1
NM_001406331.1 NP_001393260.1 GTP-binding protein SAR1a isoform 1
NM_001406332.1 NP_001393261.1 GTP-binding protein SAR1a isoform 1
NM_001406333.1 NP_001393262.1 GTP-binding protein SAR1a isoform 1
NM_001406334.1 NP_001393263.1 GTP-binding protein SAR1a isoform 1
NM_001406335.1 NP_001393264.1 GTP-binding protein SAR1a isoform 1
NM_001406336.1 NP_001393265.1 GTP-binding protein SAR1a isoform 1
NM_001406337.1 NP_001393266.1 GTP-binding protein SAR1a isoform 2
NM_001406338.1 NP_001393267.1 GTP-binding protein SAR1a isoform 3
NM_001406339.1 NP_001393268.1 GTP-binding protein SAR1a isoform 3
NM_001406340.1 NP_001393269.1 GTP-binding protein SAR1a isoform 4
NM_009120.4 NP_033146.1 GTP-binding protein SAR1a isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of cargo loading into COPII-coated vesicle IDA
IDA: Inferred from direct assay
23580231 MGI
acts upstream of or within regulation of cargo loading into COPII-coated vesicle IMP
IMP: Inferred from mutant phenotype
19966784 MGI
acts upstream of or within vesicle-mediated transport IDA
IDA: Inferred from direct assay
14728599 MGI
Cellular Component GO Annotation Evidence References Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
20086016 MGI
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
14728599 MGI
located in sarcoplasmic reticulum IDA
IDA: Inferred from direct assay
14728599 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

GTP-binding protein SAR1a

  • SAR1 gene homolog A

  • SAR1a gene homolog 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12442 SAR1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20487 Sar1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26995 Sar1a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sar1a NCBI NCBI:56681