Ccl1 - chemokine (C-C motif) ligand 1 Gene

Also Known as P500; Tca3; I-309; Scya1; Tca-3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20290

Summary

Enables cytokine activity. Acts upstream of or within chemotaxis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in heart; late tubule; and testis. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease; multiple sclerosis; pulmonary tuberculosis; and tuberculosis. Orthologous to human CCL1 (C-C motif chemokine ligand 1). [provided by Alliance of Genome Resources, Apr 2022]

Ccl1 Products (1)

mRNA Protein Name
NM_011329.3 NP_035459.1 C-C motif chemokine 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables cytokine activity IDA
IDA: Inferred from direct assay
9670926 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
9670926 MGI
Biological Process GO Annotation Evidence References Source
involved in cellular response to interleukin-17 IDA
IDA: Inferred from direct assay
30294880 MGI
acts upstream of or within chemotaxis IDA
IDA: Inferred from direct assay
9670926 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

C-C motif chemokine 1

  • CCR8 ligand

  • SIS-epsilon

  • T-cell activation protein 3

  • small-inducible cytokine A1

Recombinant Ccl1 Proteins

Cat. No. Product Name Accession Purity
HY-P73913 I-309/CCL1 Protein, Mouse (HEK293, Fc) P10146-1 (K24-C92) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P990914 Denikitug 99.00% Phase 2
HY-P991944 ZL-1218 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-122219 R243 Antagonist 98.09% Unkown
HY-124416 ML604086 Inhibitor 99.78% Unkown
HY-144197 CCR8 antagonist 1 Antagonist 99.50% Unkown
HY-RS02080 CCL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174772 Human CCL1 mRNA / Unkown
HY-RS16818 Ccl1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23259 Ccl1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ccl1 NCBI NCBI:6346