Sin3b - transcriptional regulator, SIN3B (yeast) Gene

Also Known as 2810430C10Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20467

Summary

Enables chromatin binding activity and transcription corepressor activity. Involved in cardiac muscle tissue development; negative regulation of transcription, DNA-templated; and skeletal muscle tissue development. Located in several cellular components, including autosome; nucleus; and sex chromosome. Is expressed in several structures, including central nervous system; dorsal root ganglion; eye; genitourinary system; and paraxial mesenchyme. Orthologous to human SIN3B (SIN3 transcription regulator family member B). [provided by Alliance of Genome Resources, Apr 2022]

Sin3b Products (2)

mRNA Protein Name
NM_001113248.2 NP_001106719.1 paired amphipathic helix protein Sin3b isoform 2
NM_009188.4 NP_033214.2 paired amphipathic helix protein Sin3b isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
16103876 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
8521822 MGI
enables transcription corepressor activity IDA
IDA: Inferred from direct assay
7889570 MGI
Biological Process GO Annotation Evidence References Source
involved in cardiac muscle tissue development IDA
IDA: Inferred from direct assay
10620510 MGI
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
7889570 MGI
involved in skeletal muscle tissue development IDA
IDA: Inferred from direct assay
10620510 MGI
Cellular Component GO Annotation Evidence References Source
located in X chromosome IDA
IDA: Inferred from direct assay
16787967 MGI
located in XY body IDA
IDA: Inferred from direct assay
16787967 MGI
located in Y chromosome IDA
IDA: Inferred from direct assay
16787967 MGI
located in autosome IDA
IDA: Inferred from direct assay
16787967 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
10620510 MGI
located in nucleus IDA
IDA: Inferred from direct assay
8649810 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

paired amphipathic helix protein Sin3b

  • SIN3 homolog B, transcription regulator

  • histone deacetylase complex subunit Sin3b

  • transcriptional corepressor Sin3b

  • transcriptional regulator, SIN3 yeast homolog B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12926 SIN3B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21756 Sin3b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28274 Sin3b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sin3b NCBI NCBI:23309