Tle2 - transducin-like enhancer of split 2 Gene

Also Known as Grg2; mKIAA4188

Species: Mus musculus

Gene Type: protein coding
Gene ID: 21886

Summary

Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of canonical Wnt signaling pathway and negative regulation of transcription, DNA-templated. Predicted to act upstream of or within Wnt signaling pathway. Predicted to be located in focal adhesion and nuclear body. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; integumental system; limb; and sensory organ. Orthologous to human TLE2 (TLE family member 2, transcriptional corepressor). [provided by Alliance of Genome Resources, Apr 2022]

Tle2 Products (2)

mRNA Protein Name
NM_001252401.1 NP_001239330.1 transducin-like enhancer protein 2 isoform 2
NM_019725.2 NP_062699.1 transducin-like enhancer protein 2 isoform 1
Protein Preferred Names Protein Names

transducin-like enhancer protein 2

  • groucho-related protein

  • transducin-like enhancer of split 2, homolog of Drosophila E(spl)

Orthologs Information

Species Symbol Source ID
Homo sapiens Tle2 NCBI NCBI:7089