Tlr6 - toll-like receptor 6 Gene

Mus musculus

Gene ID: 21899 | Gene type: protein coding

About Tlr6

Chromosome 5: 65,109,374-65,117,440 reverse strand.GRCm39:CM000998.3

This gene has 3 transcripts (splice variants), 190 orthologues, 23 paralogues and is associated with 9 phenotypes. Broad expression in spleen adult (RPKM 3.6), colon adult (RPKM 1.8) and 17 other tissues.

Summary

Enables diacyl Lipopeptide binding activity. Involved in several processes, including positive regulation of biosynthetic process; regulation of cytokine production; and Toll-like Receptor signaling pathway. Part of Toll-like Receptor 2-Toll-like receptor 6 protein complex. Is expressed in cerebral cortex and telencephalon. Human ortholog(s) of this gene implicated in aspergillosis; asthma; infective endocarditis; rhinitis; and tuberculosis. Orthologous to human TLR6 (toll like receptor 6). [provided by Alliance of Genome Resources, Apr 2022]

Tlr6 Products(3)

mRNA	Protein	Name
NM_001359180.2	NP_001346109.2	toll-like receptor 6 precursor
NM_001384171.1	NP_001371100.1	toll-like receptor 6 precursor
NM_011604.5	NP_035734.4	toll-like receptor 6 precursor

Tlr6 Protein Structure

LRR_RI

PLN00113

LRR_1

LRR_8

LRR_1

LRR_RI

LRRCT

TIR

0
200
400
600
795 a.a.

Protein Preferred Names

Protein Names

toll-like receptor 6

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P2036A	FSL-1 TFA	Agonist	99.76%	Unkown
HY-P2036	FSL-1	Agonist	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tlr6	NCBI	NCBI:10333

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