Usp10 - ubiquitin specific peptidase 10 Gene

Also Known as UBPO; Uchrp; mKIAA0190; 2610014N07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22224

Summary

Predicted to enable cysteine-type peptidase activity; p53 binding activity; and transmembrane transporter binding activity. Predicted to be involved in several processes, including DNA damage response, signal transduction by p53 class mediator; cellular response to interleukin-1; and negative regulation of I-kappaB kinase/NF-kappaB signaling. Predicted to act upstream of or within DNA repair and Autophagy. Predicted to be located in cytoplasm; intermediate filament cytoskeleton; and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in cytosol; early endosome; and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human USP10 (ubiquitin specific peptidase 10). [provided by Alliance of Genome Resources, Apr 2022]

Usp10 Products (2)

mRNA Protein Name
NM_001310630.1 NP_001297559.1 ubiquitin carboxyl-terminal hydrolase 10 isoform 2
NM_009462.2 NP_033488.1 ubiquitin carboxyl-terminal hydrolase 10 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
35987808 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase 10

  • deubiquitinating enzyme 10

  • ubiquintin c-terminal hydrolase related polypeptide

  • ubiquitin specific protease 10

  • ubiquitin thioesterase 10

  • ubiquitin thiolesterase 10

  • ubiquitin-specific-processing protease 10

Usp10 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Usp10 P52479 Mapt Mus musculus P10637
Anti Bait CoIP
35987808
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-175538 USP10-IN-4 / Phase 3

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-12990 Spautin-1 99.54% Unkown
HY-153886 Wu-5 99.34% Unkown
HY-163622 USP10-IN-3 98.00% Unkown
HY-125015 USP10-IN-1 Inhibitor / Unkown
HY-174329 MRT-5702D / Unkown
HY-180838 WW-104 / Unkown
HY-RS15521 USP10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15543 USP32 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17175 Usp10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23625 Usp10 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Usp10 NCBI NCBI:9100