Ugdh - UDP-glucose dehydrogenase Gene

Also Known as Udpgdh

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22235

Summary

Enables UDP-glucose 6-dehydrogenase activity. Involved in chondroitin sulfate biosynthetic process and heparan sulfate proteoglycan biosynthetic process. Acts upstream of or within gastrulation with mouth forming second. Predicted to be located in nucleoplasm. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including alimentary system; brain; integumental system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 84. Orthologous to human UGDH (UDP-glucose 6-dehydrogenase). [provided by Alliance of Genome Resources, Apr 2022]

Ugdh Products (1)

mRNA Protein Name
NM_009466.2 NP_033492.1 UDP-glucose 6-dehydrogenase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables UDP-glucose 6-dehydrogenase activity IDA
IDA: Inferred from direct assay
9737970 MGI
enables UDP-glucose 6-dehydrogenase activity IMP
IMP: Inferred from mutant phenotype
32768525 MGI
Biological Process GO Annotation Evidence References Source
involved in UDP-glucuronate biosynthetic process IMP
IMP: Inferred from mutant phenotype
32768525 MGI
involved in chondroitin sulfate biosynthetic process IMP
IMP: Inferred from mutant phenotype
14505572 MGI
acts upstream of or within gastrulation with mouth forming second IMP
IMP: Inferred from mutant phenotype
15755804 MGI
involved in gastrulation with mouth forming second IMP
IMP: Inferred from mutant phenotype
14505572 MGI
involved in heparan sulfate proteoglycan biosynthetic process IMP
IMP: Inferred from mutant phenotype
14505572 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

UDP-glucose 6-dehydrogenase

  • UDP-Glc dehydrogenase

  • UDP-GlcDH

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-E70020 UDP-Glc dehydrogenase (UGDH) / Unkown
HY-RS15422 UGDH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19969 Ugdh Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26472 Ugdh Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ugdh NCBI NCBI:7358