Aplnr - apelin receptor Gene

Mus musculus

Also known as APJ; Agtrl1; msr/apj

Gene ID: 23796 | Gene type: protein coding

About Aplnr

Chromosome 2: 84,966,569-84,970,267 forward strand.GRCm39:CM000995.3

This gene has 2 transcripts (splice variants), 172 orthologues, 9 paralogues and is associated with 26 phenotypes.

Summary

Predicted to enable apelin receptor activity. Involved in several processes, including apelin receptor signaling pathway; circulatory system development; and positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis. Acts upstream of or within regulation of gap junction assembly. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; embryo mesenchyme; and reproductive system. Orthologous to human APLNR (apelin receptor). [provided by Alliance of Genome Resources, Apr 2022]

Aplnr Products(1)

mRNA	Protein	Name
NM_011784.3	NP_035914.1	apelin receptor

Aplnr Protein Structure

7tmA_Apelin_R

0
100
200
300
377 a.a.

Protein Preferred Names

Protein Names

apelin receptor

G-protein coupled receptor APJ	MSR
angiotensin receptor-like 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (6)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P2271	MM 54	Inhibitor	99.21%	Unkown
HY-126293	Apelin agonist 1	Agonist	/	Unkown
HY-147751	APJ receptor agonist 6		/	Unkown
HY-RS00823	APLNR Human Pre-designed siRNA Set A		/	Unkown
HY-RS00824	Aplnr Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS00825	Aplnr Rat Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Aplnr	NCBI	NCBI:187

Name
Email *

	Sorry, but the email address you supplied was invalid.