Klk7 - kallikrein related-peptidase 7 (chymotryptic, stratum corneum) Gene

Also Known as SCCE; Prss6

Species: Mus musculus

Gene Type: protein coding
Gene ID: 23993

Summary

This gene encodes a member of the Kallikrein subfamily of serine proteases that are involved in diverse physiological functions such as skin desquamation, tooth enamel formation, seminal liquefaction, synaptic neural plasticity and brain function. The encoded preproprotein undergoes proteolytic cleavage of the activation peptide to generate the functional enzyme. This gene is located in a cluster of several related Kallikrein genes on chromosome 7. [provided by RefSeq, May 2016]

Klk7 Products (1)

mRNA Protein Name
NM_011872.3 NP_036002.1 kallikrein-7 preproprotein

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
is active in cornified envelope IDA
IDA: Inferred from direct assay
26644517 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kallikrein-7

  • kallikrein 7 (chymotryptic, stratum corneum)

  • kallikrein-related peptidase 7

  • serine protease 6

  • stratum corneum chymotryptic enzyme

  • thymopsin

Recombinant Klk7 Proteins

Cat. No. Product Name Accession Purity
HY-P70883 Kallikrein-7 Protein, Mouse (HEK293, His) Q91VE3 (Q22-R249) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-P4669 LM-030 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-124714 DKFZ-251 Inhibitor 95.93% Unkown
HY-150085 GSK951 Inhibitor / Unkown
HY-P11840 KLK5-IN-1 Inhibitor / Unkown
HY-RS07384 KLK6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07385 KLK7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-186007 KLK7 modulator-1 / Unkown
HY-RS17165 Klk7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23615 Klk7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24511 Klk1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992250 Anti-KLK7 Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Klk7 NCBI NCBI:5650